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Body Mass Index as A Tool for Optimizing Surgical Care in Coronary Artery Bypass Grafting Through Understanding Risks of Specific Complications.

In patients undergoing coronary artery bypass grafting, low and high BMI were risk factors of mortality associated with different types of morbidities, which may warrant tailored preventive approaches.

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Oxygenator Impact on Voriconazole in Extracorporeal Membrane Oxygenation Circuits

Further evaluations with multiple dose in vitro and in vivo investigations are needed before specific voriconazole dosing recommendations can be made for clinical application with extracorporeal membrane oxygenation.

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Antithrombin Use During Pediatric Cardiac Extracorporeal Membrane Oxygenation Admission: Insights from A National Database

Together, these results reinforce that antithrombin may not be indicated for all pediatric extracorporeal membrane oxygenation patients.

Speaking Up in the Perioperative Setting

Speaking Up in the Perioperative Setting

This article therefore looks to explain the role of Freedom to Speak Up Guardians and how this new role impacts on how concerns should be raised.

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Pharmacokinetics Alterations in Critically Ill Pediatric Patients on Extracorporeal Membrane Oxygenation: A Systematic Review

Systematic evaluations of pharmacokinetic alterations of drugs on ECMO that incorporate multidrug opportunistic trials, physiologically based pharmacokinetic modeling, and other methods are necessary for definitive dose recommendations.

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Extracorporeal Life Support Organization (ELSO): 2020 Pediatric Respiratory ELSO Guideline

This guideline describes prolonged extracorporeal life support (ECLS) and extracorporeal membrane oxygenation (ECMO), applicable to Pediatric respiratory failure.

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Development of the Adult ECMO Specialist Certification Examination

It is anticipated that ECMO facilities and ECMO service providers will incorporate the certification examination as part of their process improvement, safety, and quality assurance plans. 

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Extracorporeal Life Support in Hemorrhagic Conditions: A Systematic Review

The use of ECLS for temporary circulatory or respiratory support in critical patients with refractory hemorrhagic shock appears feasible considering tailored ECMO management strategies.

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Xenogeneic Cross-Circulation for Extracorporeal Recovery of Injured Human Lungs

Our findings suggest that cross-circulation can serve as a complementary approach to clinical EVLP to recover injured donor lungs that could not otherwise be utilized for transplantation, as well as a translational research platform for immunomodulation and advanced organ bioengineering.

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Minimally Invasive Aortic Valve Replacement on Minimally Invasive Extracorporeal Circulation: Going beyond Aesthetics.

We advocate that our multidisciplinary approach supported by multiple technologies may be associated with faster recovery and superior outcomes than conventional minimally/conventional techniques. 

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Risk Factor for Acute Kidney Injury in Patients with Chronic Kidney Disease Receiving Valve Surgery with Cardiopulmonary Bypass

To prevent postoperative AKI in CKD patients, low CPB target temperature is avoided, especially for those with high preoperative serum creatinine levels.

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Predictors of Increased Lactate in Neonatal Cardiac Surgery: The Impact of Cardiopulmonary Bypass

These results emphasized the importance of blood pressure management during CPB and the importance of the duration of circulatory arrest.

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SARS-CoV-2 Infection and Cardiovascular Disease: COVID-19 Heart

In this review, we summarise the cardiac manifestations of COVID-19 infection and propose a simplified algorithm for patient management during the COVID-19 pandemic.

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Evaluation of Point-of-Care ACT Coagulometers and Anti-Xa Activity During Cardiopulmonary Bypass

This suggests that ACT devices should not be used interchangeably, but cut-off values for safe anticoagulation during cardiopulmonary bypass should be determined for each type of device, particularly when switching supplier.

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Predicting Postoperative Delirium and Postoperative Cognitive Decline with Combined Intraoperative Electroencephalogram Monitoring and Cerebral Near-Infrared Spectroscopy in Patients Undergoing Cardiac Interventions

The results of our study show that the degree of intraoperative EEG suppression on one hand, and low rScO2 at the end of procedure on the other hand, are associated with respectively POD and POCD in patients undergoing cardiac interventions.

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Selling the Role of Salvage: Cell Salvage Past and Present

Despite the body of evidence to support the use of salvaged blood for transfusion, hesitation around its use still persists, with staff apprehension around set up of cell salvage equipment and general underestimation of intraoperative blood loss being key factors in its underuse.

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Optimization of Extracorporeal Membrane Oxygenation Therapy Using Near-Infrared Spectroscopy to Assess Changes in Peripheral Circulation: A Pilot Study

NIRS for optimizing ECMO therapy may be reliable for monitoring global circulatory status.

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Connector Sensors for Permittivity-Based Thrombus Monitoring in Extracorporeal Life Support

The connector sensor is therefore envisioned as an affordable alternative to OCT for real-time permittivity-based monitoring of thrombogenesis at tube–connector interface.

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Risk of COVID-19 Among Front-Line Health-Care Workers and the General Community: A Prospective Cohort Study.

Health-care systems should ensure adequate availability of PPE and develop additional strategies to protect health-care workers from COVID-19, particularly those from Black, Asian, and minority ethnic backgrounds.

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The Effect of Roller Head Pump on Platelet Deterioration During the Simulated Extracorporeal Circulation

We thus conclude that roller pumping induced platelet apoptosis and caused decreases in platelet count and aggregation after the recirculation.

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Haemoadsorption: Effective in Reducing Circulating Fragments of the Endothelial Glycocalyx During Cardiopulmonary Bypass in Patients Undergoing On-Pump Cardiac Surgery?

In this study representing a real-life scenario, we could demonstrate that the novel hemoadsorption device (CytoSorb®) was able to effectively adsorb HEP from the circulation if integrated in a CPB circuit.

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Extracorporeal Hemadsorption versus Glucocorticoids during Cardiopulmonary Bypass: A Prospective, Randomized, Controlled Trial

We compared intraoperative hemadsorption and methylprednisolone, with usual care, during complex cardiac surgery on CPB, for inflammatory responses, hemodynamics, and perioperative course.

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Vasoplegia After Cardiopulmonary Bypass: A Narrative Review of Pathophysiology and Emerging Targeted Therapies

This narrative review addresses both the definition, risk factors, and pathophysiology of vasoplegia and potential therapeutic interventions.

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Post Cardiotomy Extra Corporeal Membrane Oxygenation: Australian Cohort Review

Identification of poor prognostic indicators in this study may help inform the development of guidelines for the most appropriate use of this support modality.