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Gender Bias and Its Negative Impact on Cardiothoracic Surgery

Unfortunately, the surgical workforce is not close to the gender parity that has been achieved within medical schools.


Platelet Administration During Cardiopulmonary Bypass in Neonates: A Universal Therapy Applied in a Novel Way

Improved intraoperative and postoperative hemostasis was observed in neonates given platelets during the rewarming phase of cardiopulmonary bypass.

Bill N Cover|Mission Checklist

Routine Presternotomy Extracorporeal Circulation for Redo Surgery

Routine establishment of presternotomy ECC reduces the risk of injury to the mediastinal structures during reentry and facilitates easier repair in the event of structural injury during reentry or dissection.


Extracorporeal Resuscitation with Carbon Monoxide Improves Renal Function by Targeting Inflammatory Pathways in Cardiac Arrest in Pigs

Our data demonstrate improved renal function by extracorporeal CO treatment in a porcine model of cardiac arrest.

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Comparison of Three Infant Venous Reservoirs with Vacuum-assisted Venous Drainage During Varying Levels of Cardiotomy Suction

There is an adverse effect of excessive cardiotomy suction on the efficacy of vacuum-assisted venous drainage in infant hard-shell venous reservoirs.

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Differential Modulatory Effects of Propofol and Sevoflurane Anesthesia on Blood Monocyte HLA-DR and CD163 Expression During and After Cardiac Surgery with Cardiopulmonary Bypass: a Preliminary Randomized Flow Cytometry Study

Propofol seems to induce a higher postoperative fraction of the CD163highHLA-DRlow monocyte subset.

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Antithrombin Supplementation in Adult Patients Receiving Extracorporeal Membrane Oxygenation

Therapeutic anticoagulation occurred more frequently following antithrombin supplementation; however, this difference was not statistically significant. More bleeding events occurred following antithrombin supplementation while observing an increase in platelet transfusions.


Long-term Follow-up of Post-cardiac Surgery Mycobacterium Chimaera Infections: A 5-center Case Series

Given poor response to treatment and potential for delayed relapses, post-cardiac surgery M. chimaera infection warrants aggressive treatment and long-term monitoring.

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Altered Frontal White Matter Microstructure is Associated with Working Memory Impairments in Adolescents with Congenital Heart Disease: A Diffusion Tensor Imaging Study

Adolescence, which is a crucial period for prefrontal brain maturation, may offer a window of opportunity for intervention in order to support the maturation of frontal brain regions and therefore improve higher order cognitive function in patients with CHD.


Impact of Custodiol‐N Cardioplegia on Acute Kidney Injury After Cardiopulmonary Bypass

A statistical trend was found showing that AKI‐related proximal tubule swelling and cytochrome c release were diminished.


The Use of Data Science to Analyse Physiology of Oxygen Delivery in the Extracorporeal Circulation

Modern calculation tools make it possible to create a common data platform from a very large database. Using that methodology we created models of haemodynamic compounds describing tissue oxygen delivery.


Carotid artery blood flow velocities during open-heart surgery and its association with delirium

Our results suggest that higher cerebral blood flow velocities after aortic de-clamping and probably also improved brain oxygenation might be beneficial to prevent postoperative delirium.


Pharmacological Interventions to Reduce Edema Following Cardiopulmonary Bypass: A Systematic Review and Meta-analysis

To compare the effectiveness of different types of pharmacological agents to reduce organ specific edema following cardiopulmonary bypass (CPB).


Healthcare Utilization and Costs of Cardiopulmonary Complications Following Cardiac Surgery in the United States

This study demonstrates that HF and RF complication rates post cardiac surgery are substantial, and complication-related healthcare utilization over the first year following surgery results in significant incremental costs.

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Rationale and Design of the Steroids to Reduce Systemic Inflammation after Infant Heart Surgery (STRESS) Trial

The pragmatic “trial within a registry” design may provide a mechanism for conducting low cost, high efficiency trials in a heretofore-understudied patient population.


Cardiopulmonary Bypass and AKI: AKI Is Bad, So Let’s Get Beyond the Diagnosis

It is now well-established that AKI is a serious and common complication following cardiopulmonary bypass (CPB) in both children and adults.

Bill N Cover|Mission Checklist

Incidence of Reexpansion Pulmonary Edema in Minimally Invasive Cardiac Surgery

Minimally invasive cardiac surgery requires fewer blood transfusions and mediastinitis is less frequently observed compared to conventional median sternotomy surgical intervention, and it leads to earlier recovery and discharge.

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Use of Cardiopulmonary Bypass for Treatment of Malignant Hyperthermia

This suggests the potential for CPB or extracorporeal membrane oxygenation (ECMO) as a possible treatment for the symptoms of MH.


The Organ-Protective Effect of Higher Partial Pressure of Arterial Carbon Dioxide in the Normal Range for Infant Patients Undergoing Ventricular Septal Defect Repair

The aim of this study was to determine whether a higher level of partial pressure of arterial carbon dioxide (PaCO2) within the normal range in pediatric patients undergoing cardiac surgery had an organ-protective effect.


Mycobacterium Chimaera Infections: An Update

Our review aims to provide an updated account of microbiological characteristics, clinical presentation, diagnosis, and management of Mycobacterium chimaera infections, with a special focus on those developing after cardiothoracic surgery.


Impact of Cardiopulmonary Bypass Time on Postoperative Duration of Mechanical Ventilation in Patients Undergoing Cardiovascular Surgeries: A Systemic Review and Regression of Metadata

Cardiopulmonary bypass time appears to affect clinical outcomes adversely and is associated with prolonged MV. Avoiding CPB or limiting it to a minimum may decrease the days of MV required.


Hemostatic Management of Extracorporeal Circuits Including Cardiopulmonary Bypass and Extracorporeal Membrane Oxygenation

Managing bleeding on extracorporeal support requires careful monitoring and a thoughtful approach.


Clinical Utility of the Quantra® Point‐of‐care Haemostasis Analyser During Urgent Cardiac Surgery

We have shown that point‐of‐care testing using the novel Quantra system provides useful data for guiding transfusion management.

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Moderate and Deep Hypothermic Circulatory Arrest has a Comparable Effect on Acute Kidney Injury After Total Arch Replacement with Frozen Elephant Trunk Procedure in Type A Aortic Dissection

MHCA was not superior to DHCA in decreasing postoperative AKI. Thus, MHCA should not definitively replace DHCA.