Posts Tagged ‘CPB’
Platelet Function Changes during Neonatal Cardiopulmonary Bypass Surgery: Mechanistic Basis and Lack of Correlation with Excessive Bleeding
Thrombocytopenia and platelet dysfunction induced by extracorporeal blood circulation are thought to contribute to postsurgical bleeding complications in neonates undergoing cardiac surgery with cardiopulmonary bypass (CPB).
Read MoreSt Thomas’ Hospital Polarizing Blood Cardioplegia Improves Hemodynamic Recovery in a Porcine Model of Cardiopulmonary Bypass
Polarized cardiac arrest offers similar myocardial protection and enhances functional recovery in a porcine model of cardiopulmonary bypass.
Read MoreFactors Affecting Cardiovascular Physiology in Cardiothoracic Surgery: Implications for Lumped-Parameter Modeling
Cardiothoracic surgeries are complex procedures during which the patient cardiovascular physiology is constantly changing due to various factors.
Read MoreRecovery of Cefazolin and Clindamycin in In Vitro Pediatric CPB Systems
Recovery of cefazolin was high in the neonatal and infant CPB systems and moderate in the pediatric system. We found a large discrepancy between the theoretical and measured concentrations of clindamycin in all tested CPB systems.
Read MoreToddler Neurodevelopmental Outcomes Are Associated With School-Age IQ in Children With Single Ventricle Physiology
To examine whether neurodevelopment at preschool age predicts IQ levels and needs for special education services in school-age children with single ventricle (SV) physiology.
Read MoreLarge Volume Infusions of Hydroxyethyl Starch During Cardiothoracic Surgery May Be Associated With Postoperative Kidney Injury: Propensity-Matched Analysis
Intraoperative use of HES was not associated with postoperative AKI following CPB.
Read MoreWhole Blood Platelet Aggregation Kinetics Under Cardiopulmonary Bypass: A Pilot Study
Assessing the platelets’ functional status during surgery on cardiopulmonary bypass is challenging.
Read MoreMinnesota Perfusion Society (MPS) Meeting – November 1-3, 2019
You are invited to the 2019 MPS Meeting at the Double Tree – Hilton in Rochester, MN, held from November 1st – 3rd, 2019. This meeting received positive reviews from all attending in 2018, and we won’t let you down this year: “It’s so refreshing to go to a meeting and learn so many new…
Read MoreImpact of Perioperative Levosimendan Administration on Risk of Bleeding After Cardiac Surgery: A Meta-analysis of Randomized Controlled Trials
Levosimendan, a calcium sensitizer and potassium channel opener, has been demonstrated to improve myocardial function without increasing oxygen consumption and to show protective effects in other organs.
Read MoreHyperoxia During Cardiopulmonary Bypass Does Not Decrease Cardiovascular Complications Following Cardiac Surgery: the CARDIOX Randomized Clinical Trial
Data on the benefit or or harmful effects of oxygen level on ischemic reperfusion injuries in cardiac surgery are insufficient.
Read MoreEffect of Open-lung vs Conventional Perioperative Ventilation Strategies on Postoperative Pulmonary Complications After On-pump Cardiac Surgery: the PROVECS Randomized Clinical Trial
To evaluate whether a perioperative open-lung ventilation strategy prevents postoperative pulmonary complications after elective on-pump cardiac surgery.
Read MoreMUSC Update on Perfusion Conference
MUSC 21st Annual Update on Perfusion Conference. The Cardiovascular Perfusion program at MUSC will be hosting the 21st Annual Update on Perfusion Conference, October 24-26, 2019 in Charleston, SC. As one of the longest running multi-disciplinary scientific programs, The Update on Perfusion Conference features the industry’s most contemporary techniques and emerging technological advancements. Conference delegates…
Read MoreCREF 2019: The 39th Annual Cardiothoracic Surgery Symposium
The international, interdisciplinary 39th Annual Cardiothoracic Surgery Symposium (CREF 2019) focuses on the science and techniques of cardiopulmonary bypass and extracorporeal perfusion. The conference offers cutting-edge presentations, interactive discussions, case presentations, hands-on workshops, and extracurricular education on topics related to cardiac surgery, cardiopulmonary bypass, extracorporeal perfusion, and extracorporeal life support. The 39th Annual Cardiothoracic Surgery…
Read MoreAnalysis of the Critical Determinants of Renal Medullary Oxygenation
We previously developed a three-dimensional computational model of oxygen transport in the renal medulla.
Read MoreHeart Valve Operations Associated With Reduced Risk Of Death From Mitral Valve Disease But Other Operations Associated With Increased Risk of Death: A National Population-Based Case-Control Study
This study analyzed the death risk from heart valve disease with respect to the frequency of heart valve operation and other operations in patients with mitral valve disease.
Read MoreChanges in Nonlinear Dynamic Complexity Measures of Blood Pressure During Anesthesia For Cardiac Surgeries Using Cardiopulmonary Bypass
Nonlinear complexity measures computed from beat-to-beat arterial BP dynamics have shown associations with standard cardiac surgical risk indices. They reflect the physiological adaptability of a system and has been proposed as dynamical biomarkers of overall health status.
Read MoreThe Effect of Steroids in Patients Undergoing Cardiopulmonary Bypass: An Individual Patient Meta-Analysis of Two Randomized Trials
Steroids suppress the inflammatory response to cardiopulmonary bypass, but the impact on death at 30 days, myocardial infarction or injury, stroke, renal failure, respiratory failure, new atrial fibrillation, transfusion requirement, infection, and length of intensive care unit (ICU) and hospital stays are uncertain.
Read MoreEffect of Ultrafiltration on Extravascular Lung Water Assessed by Lung Ultrasound in Children Undergoing Cardiac Surgery: A Randomized Prospective Study
Ultrafiltration has been shown to decrease total body water and postoperative blood loss and improve the alveolar to arterial oxygen gradient and pulmonary compliance. This study investigated whether conventional ultrafiltration during CPB in paediatric heart surgeries influences post-bypass extravascular lung water (EVLW) assessed by lung ultrasound (LUS).
Read MoreWhat is Cardiopulmonary Bypass?
Cardiopulmonary bypass (CPB) is a technique that temporarily takes over the function of the heart and lungs during surgery, maintaining the circulation of blood and the oxygen content of the body.
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