From Italy [ 5 ] Transcatheter Aortic Valve Implantation

Editor’s Note:

Once again, just checking early morning news and chatter on Facebook, and another interesting video link rears it’s head.  This video can be found below- or on the FB group Care of heart  founded by Manoj Sharma  an Indian perfusionist that I have interacted with occasionally online.

Now this video is in Italian- so if you have an ounce of Latin in your educational or cultural background- it is enjoyable to connect the roots and dots of roots to medical terms in our own language.

The animation is great and gave me a better understanding of Transcatheter Aortic Valve implantation (TAVI).

The Old Stuff…


And… The New Stuff …

The Video  (In Italian)




Salient Points …

The New England Journal of Medicine reported this month (2010) that, for patients with severe aortic stenosis who are not candidates for surgery, Transcatheter Aortic-Valve Implantation (TAVI) using the Edwards SAPIEN valve significantly reduced mortality compared to standard treatment.

At one year, the rate of death from any cause was 30% with TAVI vs. 50.7% with standard treatment. However, this method had a higher incidence of strokes and major vascular complications compared to standard treatment.

The implantation procedure involves accessing a femoral artery, performing balloon valvuloplasty, then advancing the device across the native valve. During rapid right ventricular pacing, a balloon is inflated to deploy the valve and the frame.
Edwards is running another part of the trial comparing this valve with traditional open-heart aortic valve replacement.

Press release: The New England Journal of Medicine Publishes Transcatheter Heart Valve Trial Results

Abstract in NEJM: Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery

Related: Edwards Receives Approval to Begin U.S. Clinical Trial of Next-Generation Transcatheter Valve

Product page: Edwards SAPIEN Transcatheter Heart Valve