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Del Nido Cardioplegia is Safe and Effective Myocardial Protection in Adult Patients Undergoing Cardiac Surgery: A Single Center Experience

Del Nido cardioplegia gains increasing popularity among adult cardiac surgeons.


Peritoneal Dialysis in Pediatric Postoperative Cardiac Surgical Patients

We determined the prevalence of acute kidney injury requiring peritoneal dialysis (PD), the factors associated with early PD initiation, prolonged PD and mortality among pediatric postoperative cardiac surgical patients.

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Analysis of the Critical Determinants of Renal Medullary Oxygenation

We previously developed a three-dimensional computational model of oxygen transport in the renal medulla.

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Perfusion Management of Aortic Balloon Occlusion Technique in Total Arch Replacement With Frozen Elephant Trunk

To ensure both cerebral and lower body perfusion during total arch replacement with frozen elephant trunk, aortic balloon occlusion technique has been applied in some cases at our institute.


Establishing an ECMO Program in a Developing Country: Challenges and Lessons Learned

The ECMO (extracorporeal membrane oxygenation) Program at the American University of Beirut Medical Center was established in November 2015 as the first program serving adult and pediatric population in a low-resource setting.


Accumulations of von Willebrand Factor Within ECMO Oxygenators: Potential Indicator of Coagulation Abnormalities in Critically Ill Patients?

Clot formation within membrane oxygenators (MOs) remains a critical problem during extracorporeal membrane oxygenation (ECMO).


Is Blood a Necessary Component of the Perfusate During Isolated Limb Perfusion – a Randomized Controlled Trial

Isolated limb perfusion (ILP) is a treatment option for malignancies localized to an extremity and is performed by surgical isolation of the limb which is connected to an extracorporeal circulation system.

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Heparin-Free Extracorporeal Life Support Using Tethered Liquid Perfluorocarbon: A Feasibility and Efficacy Study

Coagulation management is the leading challenge during extracorporeal life support (ECLS) due to shear stress and foreign-surface–induced coagulation disturbance during circulation.


Detection and decontamination of Mycobacterium Chimaera and Other Non-tuberculosis Mycobacteria in Heater–cooler Devices Used in Cardiopulmonary Bypass: a Manufacturer and National Guidelines Summary, and a Potential Resolution to the Problem Requiring Further Investigation

Since 2011, invasive infections due to Mycobacterium chimaera have been diagnosed in patients with previous cardiac surgery.

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Intraoperative Autologous Blood Donation Leads to Fewer Transfusions in Cardiac Surgery

Blood conservation with antifibrinolytics, topical hemostatics, and strict transfusion triggers are becoming commonplace in cardiac surgery.

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Impact of Age of Packed RBC Transfusion on Oxygenation in Patients Receiving Extracorporeal Membrane Oxygenation

To determine the effect of age of packed RBCs on tissue oxygenation in children receiving extracorporeal membrane oxygenation support.

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Current Evidence and Future Directions of Tranexamic Acid Use, Efficacy, and Dosing for Major Surgical Procedures

Tranexamic acid reduces blood loss and transfusion requirements with no significant thrombotic adverse effects.


Serum Lactate Poorly Predicts Central Venous Oxygen Saturation in Critically Ill Patients: a Retrospective Cohort Study

Serum lactate and central venous oxygen saturation (ScvO2) are commonly used and commonly recommended as markers of tissue oxygenation in shock states.


Ex Vivo Heart Perfusion for 72 Hours Using Plasma Cross Circulation

Preservation of a donor heart for transplantation is limited to 6–8 hours.

ECMO Summary

Extracorporeal Membrane Oxygenation: Indications, Technique and Contemporary Outcomes

Extracorporeal membrane oxygenation (ECMO) is an advanced form of temporary life support, to aid respiratory and/or cardiac function. It has been used since the early 1970s and is based on cardiopulmonary bypass technology and diverts venous blood through an extracorporeal circuit and returns it to the body after gas exchange through a semi-permeable membrane.

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Association Between Anemia and Blood Transfusion With Long-term Mortality After Cardiac Surgery

The aim of this study was to investigate the interactions between preoperative anemia and RBC transfusion and their effect on the long-term survival of patients undergoing cardiac surgery.


Neurologic Outcomes in Patients Who Undergo Extracorporeal Cardiopulmonary Resuscitation

This study aimed to develop a risk prediction model for neurologic outcomes in patients who underwent extracorporeal cardiopulmonary resuscitation (ECPR).


Use of Quality of Life in Cardiovascular Surgery in Coronary Artery Bypass Grafting: Validation, Reproducibility, and Quality of Life in One Year of Follow-Up

The objectives of this study are to validate the Quality of Life in Cardiovascular Surgery (QLCS) questionnaire and to observe the evolution of quality of life in the first year of postoperative follow-up of patients who underwent coronary artery bypass grafting (CABG).

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A Century of Heparin

The year 2018 was the centennial of the naming of heparin by Emmett Holt and William Howell and the 102nd anniversary of Jay McLean’s discovery of an anticoagulant heparphosphatide at Johns Hopkins Hospital in Baltimore.

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BloodSurf 2017: News From the Blood-biomaterial Frontier

From stents and large-diameter vascular grafts, to mechanical heart valves and blood pumps, blood-contacting devices are enjoying significant clinical success owing to the application of systemic antiplatelet and anticoagulation therapies.


Nitric Oxide Attenuates the Inflammatory Effects of Air During Extracorporeal Circulation

Cardiopulmonary bypass causes a systemic inflammatory response reaction that may contribute to postoperative complications. One cause relates to the air/blood interface from the extracorporeal circuit. The modulatory effects of blending nitric oxide (NO) gas into the ventilation/sweep gas of the membrane lung was studied in a porcine model of air-induced inflammation in which NO gas was added and compared with controls with or without an air/blood interface.


Left Ventricular Decompression on Veno-arterial Extracorporeal Membrane Oxygenation With Intra-aortic Balloon Counterpulsation

There has been growing recognition of the favorable and unfavorable hemodynamic effects of this therapy and recent interest in the use of other percutaneous circulatory support devices to offset some of the potentially harmful hemodynamic effects.

ECMO Summary

Structured Review of Post-cardiotomy Extracorporeal Membrane Oxygenation: Part 2 – Pediatric Patients

Veno-arterial extracorporeal membrane oxygenation (ECMO) is established therapy for short-term circulatory support for children with life-treating cardiorespiratory dysfunction.

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The Effect of Various Blood Management Strategies on Intraoperative Red Blood Cell Transfusion in First-time Coronary Artery Bypass Graft Patients

The present study evaluated the distribution of intraoperative interventions in patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass.