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cover, cpb, cardiopulmonary bypass

Comparative Effects of On-Pump Versus Off-Pump Coronary Artery Bypass Grafting Surgery on Serum Cytokine and Chemokine Levels

Cardiopulmonary pump in patients under CABG surgery can activate systemic inflammation and the changes of serum cytokines levels in off-pump CABG were lower compared with on-pump CABG.


Extracorporeal Membrane Oxygenation for COVID-19: Evolving Outcomes from the International Extracorporeal Life Support Organization Registry

Mortality after ECMO for patients with COVID-19 worsened during 2020. These findings inform the role of ECMO in COVID-19 for patients, clinicians, and policy makers.

perfusion timers

Anesthetic Management of Successful Extracorporeal Resuscitation After Six Hours of Cardiac Arrest Due to Severe Accidental Hypothermia

The case of a patient who experienced cardiac arrest due to severe AH and was resuscitated for more than six hours using extracorporeal life support recently was published. Herein that case is reviewed, with the anesthetic management during cannulation detailed.


Antifibrinolytic Drugs for the Prevention of Bleeding in Pediatric Cardiac Surgery on Cardiopulmonary Bypass: A Systematic Review and Meta-analysis

The available data demonstrate efficacy for all 3 antifibrinolytic drugs. Therefore, the agent with the most favorable safety profile should be used. As sufficient data are lacking, large comparative trials are warranted to assess the relative safety and appropriate dosing regimens in pediatrics.

cover, miecc, minimal invasive, hybrid

Incidence of Postoperative Pulmonary Complications in Patients Undergoing Minimally Invasive Versus Median Sternotomy Valve Surgery: Propensity Score Matching

MIVS for isolated valve surgery reduces the risk of PPCs compared with the FS approach.

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Clinical Characteristics Between Survivors and Nonsurvivors of COVID-19 Patients Requiring Extracorporeal Membrane Oxygenation (ECMO) Support: A Systematic Review and Meta-Analysis

We found advanced age, multiple comorbidities, lower pre-ECMO pH, greater RRT, and vasopressor requirements, and bleeding are predictors of death in COVID-19 patients requiring ECMO support. The duration of MV before ECMO support initiation and total ECMO support duration was similar among survivors and nonsurvivors. Our study results have important clinical implications when considering ECMO support in critically ill COVID-19 patients.

cover, bloodgas, heart

Use of Laboratory Testing for Prediction of Postoperative Bleeding Volume in Cardiovascular Surgery

These results suggest that several clinical and routine laboratory parameters of coagulation were individually associated with bleeding volume during cardiovascular surgery. Determining the patterns of coagulopathy may potentially help guide transfusion during cardiovascular surgery.

Artwork - Stormy Cells

A Uniform and Robust Bioinspired Zwitterion Coating for Use in Blood-Contacting Catheters with Improved Anti-Inflammatory and Antithrombotic Properties

Thus, it is envisioned that this biomimetic erythrocyte membrane surface strategy will provide a promising way to mitigate inflammation and thrombosis caused by the use of blood-contacting catheters.


A Pumpless Artificial Lung without Systemic Anticoagulation: the Nitric Oxide Surface Anticoagulation System

The NOSA system provides NO flux across a gas-exchange membrane of a pumpless artificial lung at a similar rate as native vascular endothelium and achieves effective local anticoagulation of an artificial lung circuit for 24 h.

cover, cpb, bypass, hlm, syringe, sampling

Methylprednisolone in Pediatric Cardiac Surgery: Is There Enough Evidence?

MP may provide a small benefit that is easily abolished by patient characteristics, surgical techniques, and perfusion management. The lack of evidence leads to large differences in practice between and within countries, and even within hospitals, so

Machine for cardiopulmonary bypass

Comparison of Microplegia Solution and Del Nido Cardioplegia Solution in Coronary Artery Bypass Grafting Surgery: Which One is More Effective?

In light of short-term results, we can say that Del Nido cardioplegia provides better myocardial protection than microplegia. In addition, Del Nido cardioplegia can be given as a single dose for 90 minutes of cross-clamp time and therefore can be preferred to increase surgical comfort and reduce cross-clamp times.

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Management and Outcomes of Cardiogenic Shock in Cardiac ICUs With Versus Without Shock Teams

In this multicenter observational study, centers with shock teams were more likely to obtain invasive hemodynamics, use advanced types of MCS, and have lower risk-adjusted mortality. A standardized multidisciplinary shock team approach may improve outcomes in CS.


Interrelations of Intraoperative Changes in Cerebral Tissue Oxygen Saturation with Brain Volumes and Neurodevelopment Outcome After the Comprehensive Stage II Procedure in Infants With Hypoplastic Left Heart Syndrome: A Retrospective Cohort Study

The correlation between ScerebO2 and brain volumes measured by MRI pointed out a possible importance of neuroprotective strategies aimed at optimizing ScerebO2 during complex congenital heart surgery. That no correlation between ScerebO2 and Bayley III Score was found suggested multifactorial causes for neurologic outcome in children with congenital heart defects.


The Impact of del Nido Cardioplegia Solution on Blood Morphology Parameters

The del Nido cardioplegia does not decrease blood morphology parameters when compared to cold blood cardioplegia and may be used alternatively regardless of bleeding and coagulopathy risk.

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COVID Convalescence—A Boon or Bane in Cardiac Surgery?: A “Second Hit” Hypothesis

A “convalescent COVID-19” patient with “first hit” at primary infection, encountering a “second hit” of surgery and perioperative insults, might have a hyperimmune response. This “second hit” hypothesis should be considered when COVID-19 convalescent (COVID-19 symptomatic or asymptomatic) patients undergo cardiac surgery and present with unusual complicatio

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Predictors and Outcomes of Coronary Artery Bypass Grafting: A Systematic and Untargeted Analysis of More Than 120,000 Individuals and 1,300 Disease Traits

Known CVD risk factors associate most strongly with incident CABG. However, CABG is associated with increased risk of several, somewhat unexpected, non-CVD traits. More detailed study of these links is warranted to establish potential causality and pathogenesis.

cover, ecmo, ecls, oxy

Bi-Caval Dual Lumen Catheter for Pediatric Patients Undergoing Venovenous Extracorporeal Membrane Oxygenation

Chest X-ray and transthoracic echocardiography showed good catheter positioning, and the recirculation rate was also dramatically decreased to 0%. The patient continuously received treatment for ARDS under the dependence of VV-ECMO.


Nitrogen Oxide-Added Extracorporeal Membrane Oxygenation for Treating Critical Acute Heart Failure after Cardiac Surgery

For the first time, venoarterial ECMO with supply of gaseous nitric oxide into the extracorporeal circuit was used to support blood circulation after cardiac surgery. This made it possible to ensure the survival of the patient with critical ischemia-reperfusion injury developed after the surgery.


The Susceptibility of the Aortic Root: Porcine Aortic Rupture Testing Under Cardiopulmonary Bypass

This unique porcine model shows that the aortic root is most susceptible to failure at high continuous aortic pressures, supported histologically by different changes in collagen content and subtypes in the aortic root. With further analysis, this information could guide management of the aortic root in disease.

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Strategies to Prevent Acute Kidney Injury after Pediatric Cardiac Surgery – A Network Meta-Analysis

Current evidence from randomized controlled trials does not support the efficacy of most strategies to prevent AKI in the pediatric population, apart from limited evidence for dexmedetomidine and remote ischemic preconditioning.


Viscoelastic Hemostatic Assays: Update on Technology and Clinical Applications

In this article, we will review recent advances in TEG and ROTEM technology and introduce the Quantra Hemostasis Analyzer device.


Beneficial Effect of Prone Positioning During Venovenous Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019

Our study highlights that prone positioning during venovenous extracorporeal membrane oxygenation support for refractory coronavirus disease 2019-related acute respiratory distress syndrome is associated with reduced mortality. Given the observational nature of the study, a randomized controlled trial of prone positioning on venovenous extracorporeal membrane oxygenation is needed to confirm these findings.

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Tranexamic Acid after Cardiopulmonary Bypass Does Not Increase Risk of Postoperative Seizures: A Retrospective Study

Administering TXA after bypass may reduce requirements for blood products without increasing risk of seizures following cardiac surgery.


Cardiac Surgery under Cardiopulmonary Bypass in Pregnancy: Report of Four Cases

Heart disease during pregnancy should be treated actively and proactively when the patient has obvious symptoms. Heart valve replacement under CPB will be the first choice, and this may become the primary surgical treatment for symptomatic heart disease during pregnancy.