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Clinical Challenge: Effective De-Airing designed to Reduce the Risk of Air Embolism

Clinical Challenge: Effective De-Airing designed to Reduce the Risk of Air Embolism

Clinical Challenge: Effective De-Airing designed to Reduce the Risk of Air Embolism. Video presentation from Sanibel Symposium 2018 (18:10 minutes).

Hydrogen Peroxide Monitoring and Design Upgrade Customer Letter

Hydrogen Peroxide Monitoring and Design Upgrade Customer Letter

The purpose of this letter is to advise you that LivaNova Deutschland GmbH (“LivaNova” or “the Company”) is executing a voluntary medical device correction for the 3T Heater-Cooler Systems (“3T”). This letter describes immediate action to be taken by you.

Emergent Cardiac Surgery During Transcatheter Aortic Valve Implantation (TAVI): A Weighted Meta-Analysis of 9,251 Patients From 46 Studies

Emergent Cardiac Surgery During Transcatheter Aortic Valve Implantation (TAVI): A Weighted Meta-Analysis of 9,251 Patients From 46 Studies

Refinement in transcatheter aortic valve implantation (TAVI) technology should not only focus on miniaturisation and improving flexibility of the delivery systems and/or devices -which may have the potential for decreasing aortic dissection, annular rupture, and tamponade- but also incorporate modifications to prevent embolisation/dislocation of the valve.

Implementation of a Mechanical CPR Device in a Physician Staffed HEMS – A Prospective Observational Study

Implementation of a Mechanical CPR Device in a Physician Staffed HEMS – A Prospective Observational Study

In this prospective, observational study we describe the incidence and characteristics of out of hospital cardiac arrest (OHCA) cases who received mechanical CPR, after the implementation of a mechanical CPR device.

Hybrid Extracorporeal Membrane Oxygenation

Hybrid Extracorporeal Membrane Oxygenation

Veno-venous (VV) and veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) therapy is widely used in critically ill patients with refractory cardiogenic shock and cardiac arrest or suffering from severe respiratory failure. Besides traditional ECMO cannulation, changes in patients’ conditions or the occurrence of specific complications (i.e., cerebral hypoxia or left ventricular dilation) may require modifications in cannulation strategies or the combination of ECMO with additional invasive or minimally invasive procedures, to improve organ function and ECMO efficiency.

Early LVAD Implantation in a Patient with Left Ventricular Failure after Aortic Dissection with Left Main Stem Involvement

Early LVAD Implantation in a Patient with Left Ventricular Failure after Aortic Dissection with Left Main Stem Involvement

Coronary involvement in aortic dissection heralds a poor outcome. Involvement of the left main stem may lead to left ventricular (LV) failure requiring mechanical circulatory support.

VV Extracorporeal Life Support for the Third Millennium: Will We Need Anticoagulation?

VV Extracorporeal Life Support for the Third Millennium: Will We Need Anticoagulation?

This review focuses on present day techniques for anticoagulation for ECLS and what future surface modifications may do to obviate the use of systemic anticoagulation entirely.

Ex Vivo Lung Perfusion Review of a Revolutionary Technology

Ex Vivo Lung Perfusion Review of a Revolutionary Technology

Ex vivo lung perfusion (EVLP) is widely expanding technology to assess and prepare the lungs who are considered marginal for transplantation.

Diagnostic and Therapeutic Medical Devices for Safer Blood Management in Cardiac Surgery: Systematic Reviews, Observational Studies and Randomised Controlled Trials

Diagnostic and Therapeutic Medical Devices for Safer Blood Management in Cardiac Surgery: Systematic Reviews, Observational Studies and Randomised Controlled Trials

This study evaluated the clinical effectiveness and cost-effectiveness of medical devices used as diagnostic and therapeutic tools for the management of anaemia and bleeding in cardiac surgery.

Thromboelastography for Predicting Bleeding in Patients with Aortic Stenosis Treated with TAVI

Thromboelastography for Predicting Bleeding in Patients with Aortic Stenosis Treated with TAVI

Bleeding complications are frequent and independently impact mortality after TAVI. Thromboelastography (TEG) measures viscoelastic properties of clot formation and is currently best known for perioperative management to reduce blood transfusion in cardiac surgery.

Association Between Platelet Count and Postoperative Blood Loss in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass and Fresh Frozen Plasma Administration Guided by Thromboelastometry

Association Between Platelet Count and Postoperative Blood Loss in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass and Fresh Frozen Plasma Administration Guided by Thromboelastometry

Coagulopathy after cardiopulmonary bypass (CPB) is caused by multiple factors, including reduced coagulation factors and a low platelet count.

Prediction of Postoperative Blood Loss Using Thromboelastometry in Adult Cardiac Surgery: Cohort Study and Systematic Review

Prediction of Postoperative Blood Loss Using Thromboelastometry in Adult Cardiac Surgery: Cohort Study and Systematic Review

The aim was to evaluate the predictive value of thromboelastometry for postoperative blood loss in adult cardiac surgery with cardiopulmonary bypass.

Use of a Flowable Haemostat Versus an Oxidised Regenerated Cellulose Agent in Primary Elective Cardiac Surgery: Economic Impact from a UK Healthcare Perspective

Use of a Flowable Haemostat Versus an Oxidised Regenerated Cellulose Agent in Primary Elective Cardiac Surgery: Economic Impact from a UK Healthcare Perspective

We investigated the economic impact of the use of a flowable haemostatic agent (Floseal) compared with non-flowable oxidised regenerated cellulose (ORC) agent in primary elective cardiac surgeryfrom the perspective of the UK National Health Service (NHS).

Point-of-Care Washing of Allogeneic Red Blood Cells for the Prevention of Transfusion-Related Respiratory Complications (WAR-PRC): A Protocol for a Multicenter Randomised Clinical Trial in Patients Undergoing Cardiac Surgery

Point-of-Care Washing of Allogeneic Red Blood Cells for the Prevention of Transfusion-Related Respiratory Complications (WAR-PRC): A Protocol for a Multicenter Randomised Clinical Trial in Patients Undergoing Cardiac Surgery

Point-of-care (POC) washing of allogeneic RBCs may remove biological response modifiers (BRMs), thereby mitigating their impact on post-transfusion respiratory complications.

Effects of Cerebral Near-Infrared Spectroscopy on the Outcome of Patients Undergoing Cardiac Surgery: A Systematic Review of Randomised Trials

Effects of Cerebral Near-Infrared Spectroscopy on the Outcome of Patients Undergoing Cardiac Surgery: A Systematic Review of Randomised Trials

Goal-directed optimisation of cerebral oxygenation using near-infrared spectroscopy (NIRS) during cardiopulmonary bypass is widely used. We tested the hypotheses that the use of NIRS cerebral oximetry results in reductions in cerebral injury (neurocognitive function, serum biomarkers), injury to other organs including the heart and brain, transfusion rates, mortality and resource use.

Acute Biventricular Mechanical Circulatory Support for Cardiogenic Shock

Acute Biventricular Mechanical Circulatory Support for Cardiogenic Shock

The aim of this study was to explore the clinical utility of percutaneously delivered BiPella as a novel acute mechanical support strategy for patients with cardiogenic shock complicated by biventricular failure.

Effects of Cerebral Near-Infrared Spectroscopy on the Outcome of Patients Undergoing Cardiac Surgery: A Systematic Review of Randomised Trials

Effects of Cerebral Near-Infrared Spectroscopy on the Outcome of Patients Undergoing Cardiac Surgery: A Systematic Review of Randomised Trials

Goal-directed optimization of cerebral oxygenation using near-infrared spectroscopy (NIRS) during cardiopulmonary bypass is widely used. We tested the hypotheses that the use of NIRS cerebral oximetry results in reductions in cerebral injury (neurocognitive function, serum biomarkers), injury to other organs including the heart and brain, transfusion rates, mortality and resource use.

Argatroban for an Alternative Anticoagulant in HIT during ECMO

Argatroban for an Alternative Anticoagulant in HIT during ECMO

Extracorporeal membrane oxygenation (ECMO) have become more frequently used in daily ICU practice, heparin-induced thrombocytopenia (HIT) is a rare but life-threatening complication while on extracorporeal membrane oxygenation (ECMO).

Risk Factors of Perioperative Intra-Aortic Balloon Pump Complications in Cardiac Surgery: A 12-Year Single-Institution Analysis

Risk Factors of Perioperative Intra-Aortic Balloon Pump Complications in Cardiac Surgery: A 12-Year Single-Institution Analysis

This study investigated the incidence and risk factors of the complications in perioperative intra-aortic balloon pump (IABP) supported cardiac surgical patients.

Analysis of Platelet-Rich Plasma Extraction: Variations in Platelet and Blood Components Between 4 Common Commercial Kits

Analysis of Platelet-Rich Plasma Extraction: Variations in Platelet and Blood Components Between 4 Common Commercial Kits

Platelet-rich plasma (PRP) has been extensively used as a treatment in tissue healing in tendinopathy, muscle injury, and osteoarthritis. However, there is variation in methods of extraction, and this produces different types of PRP.

Concentrated Bone Marrow Aspirate for the Treatment of Chondral Injuries and Osteoarthritis of the Knee: A Systematic Review of Outcomes

Concentrated Bone Marrow Aspirate for the Treatment of Chondral Injuries and Osteoarthritis of the Knee: A Systematic Review of Outcomes

The purpose of this study was to provide a systematic review regarding the outcomes of bone marrow aspirate concentrate used for the treatment of chondral defects and osteoarthritis of the knee.

Bone Marrow Aspirate Concentrate for the Treatment of Osteochondral Lesions of the Talus: A Systematic Review of Outcomes

Bone Marrow Aspirate Concentrate for the Treatment of Osteochondral Lesions of the Talus: A Systematic Review of Outcomes

The goal of this perform a systematic review on the outcomes of bone marrow aspirate concentrate (BMAC) for the treatment of chondral defects and osteoarthritis (OA) of the talus.

Extracorporeal Membrane Oxygenation Support in Post-Traumatic Cardiopulmonary Failure: A 10-Year Single Institutional Experience

Extracorporeal Membrane Oxygenation Support in Post-Traumatic Cardiopulmonary Failure: A 10-Year Single Institutional Experience

Patients with multiple traumas associated with cardiopulmonary failure have a high mortality rate; however, such patients can be temporarily stabilized using extracorporeal membrane oxygenation (ECMO), providing a bridge to rescue therapy.

The Basic Science of Bone Marrow Aspirate Concentrate in Chondral Injuries

The Basic Science of Bone Marrow Aspirate Concentrate in Chondral Injuries

There has been great interest in bone marrow aspirate concentrate (BMAC) as a cost effective method in delivering mesenchymal stem cells (MSCs) to aid in the repair and regeneration of cartilage defects.