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Antifactor Xa Monitoring and Hematologic Complications of Pediatric Extracorporeal Membrane Oxygenation

Management of anticoagulation based on anti-Xa levels appears to be as effective as management based on ACT results.


Comparison of Three Autotransfusion Devices for Utilization in the Pediatric Population

Each device proved effective within our pediatric population.

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Hemodynamics of Neonatal Double Lumen Cannula Malposition

Results obtained through computational fluid dynamics methodology can provide valuable foresight in assessing the performance of the dual lumen cannula in patient-specific configurations.


Effects of Cardiopulmonary Bypass with Low-priming Volume on Clinical Outcomes in Children Undergoing Congenital Heart Disease Surgery

The usage of PRBCs in CPB with low-priming volume decreased significantly, but the postoperative Hb concentration and platelet count could still be maintained at a high level, improving the use efficiency of PRBCs. CPB with low-priming volume did not affect the postoperative recovery of patients, so it is worthy of continuous promotion and optimization.


Neuromonitoring Modalities in Pediatric Cardiac Anesthesia: A Review of the Literature

This review provides a brief overview of the current knowledge regarding neurodevelopmental outcomes in children with CHD and summarizes the evidence for the use of the following 4 neuromonitoring modalities: transcranial Doppler, cerebral near-infrared spectroscopy, standard electroencephalography, and processed electroencephalography.


Comparison of Outcomes of the Use of Del Nido and St. Thomas Cardioplegia in Adult and Paediatric Cardiac Surgery: a Systematic Review and Meta-analysis

Del Nido cardioplegia may be a viable alternative to the use of St. Thomas cardioplegia in both adult and paediatric patients, providing similar postoperative outcomes while also affording the additional advantage of shorter aortic cross-clamp time and cardiopulmonary bypass time (in adult cardiac surgery) and decreased rates of defibrillation (in both adult and paediatric cardiac surgery).

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Childhood Extracorporeal Membrane Oxygenation Survivors: Parents Highlight Need for Structured Follow-Up and Support After Hospital Discharge

A proportion of children who have undergone extracorporeal membrane oxygenation treatment have needs that are not being met, with variable access to service provision.


Towards Integrative Neuromonitoring of the Surgical Newborn – A Systematic Review

Neuromonitoring with the techniques currently used will neither help our understanding of the altered neonatal pathophysiology, nor enable early detection of deviation from the norm. The modalities lack specificity and are not related to clinical (long-term) outcome or prognosis. Accordingly, we were unable to draw up a monitoring guideline.

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Validation of the ‘Paediatric Extracorporeal Membrane Oxygenation Prediction’ Model in a UK Extracorporeal Membrane Oxygenation Centre

This small single-centre study with a small number of events was unable to validate the paediatric extracorporeal membrane oxygenation prediction-model of risk-adjustment. Although this remains the most promising of all the available models, further validation in larger data sets and/or refinement may be required before widespread use.

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Extracorporeal Membrane Oxygenation Support for Pediatric Burn Patients: Is It Worth the Risk?

Extracorporeal membrane oxygenation could be considered as an additional level of support for the pediatric burn population, especially in the setting of respiratory failure.


Minimally Invasive Cardiac Surgical Procedures in Children

In this summary we will review the approaches that have been described and comment on the evidence that they achieve the desired goal of minimizing the trauma of the surgical procedure and enhancing recovery.

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Clinical Application of a New Ternary Polymer, SEC-1 coat™, for Pediatric Cardiopulmonary Bypass Circuits: a Prospective Randomized Pilot Study

SEC-1 coat™ for cardiopulmonary bypass circuits have good biocompatibility with regard to platelet preservation and in terms of attenuating inflammatory reaction or coagulation activation during pediatric cardiac surgery.


Hyperlactatemia: An Update on Postoperative Lactate

In patients with evidence of adequate perfusion, a type B component is often associated with a concomitant balanced (normal anion gap) metabolic acidosis and hyperglycemia. These patients will benefit from a more nuanced approach to their type B hyperlactatemia, as many will have a benign course and may be managed expectantly.


Factors Associated With Survival Following Extracorporeal Cardiopulmonary Resuscitation in Children

Efforts to improve systemic output before and after institution of ECPR might mitigate some of the significant risk factors for mortality.

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ECMO as a Platform for Rapid Ammonia Removal in a Neonate With Multienzyme Urea Cycle Disorder

This case will add to the existing scant literature supporting the use of ECMO as a platform for rapid removal of serum ammonia.

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Deep Hypothermic Circulatory Arrest Activates Neural Precursor Cells in Neonatal Brain

Neonatal piglet ACP at 18°C or 25°C provides adequate protection from increased brain cellular apoptosis. In contrast to ACP however, DHCA induces brain Nestin expression, indicating activation of neural progenitor cells and the potential of altering neonatal neurodevelopmental progression.


Neck Cannulation for Bypass in Redo Sternotomy in Children and Adults with Congenital Heart Disease

Cannulation of the right neck vessels for peripheral cardiopulmonary bypass prior to high-risk redo sternotomy in children and adults with congenital heart disease is a safe and effective strategy.

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COVID-19 FAQ’s in Pediatric Cardiac Surgery

The purpose of this review is to succinctly summarize frequently asked questions related to COVID-19 as it relates to children with congenital heart disease.

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COVID-19: Crisis Management in Congenital Heart Surgery

The safety of our patients, healthcare providers, and our communities is our chief concern. This document is not meant to be a guideline but is designed to provide guidance for decision-making as we face unparalleled challenges related to congenital cardiac surgery care during this pandemic.


Are Blood Products Routinely Required in Pediatric Heart Surgery?

The majority of children with a BW > 8.5 kg required no blood products and those with a BW ≤ 8.5 kg required only 1 unit of blood, to prime the cardiopulmonary bypass circuit.


The Utility of Albumin Level as a Marker of Postoperative Course in Infants Undergoing Repair of Congenital Heart Disease

In summary, we found that preoperative and POD#2 albumin levels predicted prolonged and complicated postoperative course.


Cell-Cycle Arrest Biomarkers Usefulness for Cardiac Surgery-Related Acute Kidney Injury in Neonates and Infants

These findings question the usefulness of (TIMP-1) × (IGFBP-7) for the prediction of cardiac surgery-related acute kidney injury in neonates and infants when measured within 3 hours of cardiopulmonary bypass.

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Frequency and Outcomes of Elevated Perioperative Lactate Levels in Adult Congenital Heart Disease Patients Undergoing Cardiac Surgery

Currently there is insufficient evidence to use lactate levels as a predictor of outcomes in adult patients with congenital heart disease undergoing cardiac surgery.

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In Vitro Recovery of Sufentanil, Midazolam, Propofol, and Methylprednisolone in Pediatric Cardiopulmonary Bypass Systems

The present in vitro experiment with neonatal, infant, and pediatric CPB systems shows a variable recovery of routinely used drugs with significant differences between drugs, but not between system categories (with the exception of propofol).