Validation Study of the Transfusion Risk and Clinical Knowledge (TRACK) Tool in Cardiac Surgery Patients: A Retrospective Analysis
The Transfusion Risk and Clinical Knowledge (TRACK) scoring system has been developed for predicting perioperative blood transfusions. However, the TRACK score needs to be validated externally in the US population. The primary objective of this study is to validate TRACK at the authors’ institution.
The Database Dilemma: An Imperfect but Critical Tool to Improve Quality and Benchmark Outcomes (Ed.)
The Society of Thoracic Surgeons (STS) database was created in 1989 as a patient safety initiative for adults undergoing cardiothoracic surgery. In 2005, pediatric and congenital cardiac patient data began being collected by a registry operated by the Congenital Cardiac Anesthesia Society.
Discriminatory Power of Scoring Systems for Outcome Prediction in Patients With Extracorporeal Membrane Oxygenation Following Cardiovascular Surgery
Although extracorporeal membrane oxygenation (ECMO) represents a rapidly evolving treatment option in patients with refractory heart or lung failure, survival remains poor and appropriate risk stratification challenging because established risk prediction models have not been validated for this specific population.
Red Blood Cell Dysfunction: a New Player in Cardiovascular Disease
The primary role of red blood cells (RBCs) is to transport oxygen to the tissues and carbon dioxide to the lungs. However, emerging evidence suggests an important role of the RBC beyond being just a passive carrier of the respiratory gases.
Quality of Life After Coronary Bypass: a Multicentre Study of Routinely Collected Health Data in the Netherlands
In this study, our aim was to explore how coronary artery bypass grafting affects quality of life, and how this varies with age, particularly with patients at risk of deterioration.
Cardiopulmonary Bypass and Dual Antiplatelet Therapy: a Strategy to Minimise Transfusions and Blood Loss
Patients with preoperative dual antiplatelet therapy prior to coronary artery bypass surgery are at risk of bleeding and blood component transfusion. We hypothesise that an optimised cardiopulmonary bypass strategy reduces postoperative blood loss and transfusions.
In-vitro Performance of a Low Flow Extracorporeal Carbon Dioxide Removal Circuit
Extracorporeal gas exchange requires the passage of oxygen and carbon dioxide (CO2) across an artificial membrane. Current European Union regulations do not require the transfer to be assessed in models using clinically relevant haemoglobin, making it difficult for clinicians to understand the CO2 clearance of a membrane, and how it changes in relation to sweep gas flow through the membrane.
Postoperative Pain Management in Pediatric Patients Undergoing Cardiac Surgery: Where Are We Heading?
Adequate postoperative pain management is crucial in pediatric patients undergoing cardiac surgery because pain can lead to devastating short- and long-term consequences. This review discusses the limitations of current postoperative pain assessment and management in children after cardiac surgery, the obstacles to providing optimal treatment, and concepts to consider that may overcome these barriers.
Neurological Complications After Cardiac Surgery Anesthetic Considerations Based on Outcome Evidence
Neurological complications after cardiac surgery remain prevalent. This review aims to discuss the modifiable and outcome-relevant risk factors based on an up-to-date literature review, with a focus on interventions that may improve outcomes.
Predicting Outcome After Out-of-Hospital Cardiac Arrest: Lactate, Need for Vasopressors, and Cytochrome c
Outcome prediction after out-of-hospital cardiac arrest (OHCA) is difficult. We hypothesized that lactate and need for vasopressors would predict outcome, and that addition of a mitochondrial biomarker would enhance performance of the tool.
Multiple Organ Dysfunction Syndrome
Multiple organ dysfunction syndrome (MODS) is one of the most common syndromes of critical illness and the leading cause of mortality among critically ill patients. Multiple organ dysfunction syndrome is the clinical consequence of a dysregulated inflammatory response, triggered by clinically diverse factors with the main pillar of management being invasive organ support.
Comparison of Machine Learning Methods With National Cardiovascular Data Registry Models for Prediction of Risk of Bleeding After Percutaneous Coronary Intervention
Can machine learning techniques, bolstered by better selection of variables, improve prediction of major bleeding after percutaneous coronary intervention (PCI)?
Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly
Aspirin is a well-established therapy for the secondary prevention of cardiovascular events. However, its role in the primary prevention of cardiovascular disease is unclear, especially in older persons, who have an increased risk.
Toward Precision Policy — The Case of Cardiovascular Care
The U.S. health care system is in the midst of a transition toward delivery of high-value rather than volume-based health care.
Comparison Of The Effect Of 80 vs 40 mg Atorvastatin In Patients With Isolated Coronary Artery Bypass Graft Surgery: A Randomized Clinical Trial
Atorvastatin can decrease cardiac injury after coronary artery bypass graft (CABG) surgery. We compared the effects of 80 and 40 mg of atorvastatin per day on the levels of cardiac troponin T (cTnT) and creatine kinase-MB (CK-MB) after an isolated CABG.
Association Between Cyanosis, Transfusion, and Thrombotic Complications in Neonates and Children Undergoing Cardiac Surgery
Children with congenital heart defects are at increased risk for perioperative bleeding and postoperative thrombosis. In this study, the authors sought to develop a predictive model for postoperative thrombotic complications that integrates intraoperative bleeding and the requirement for allogenic blood products in addition to known patient and surgical characteristics.
Changes in Nonlinear Dynamic Complexity Measures of Blood Pressure During Anesthesia For Cardiac Surgeries Using Cardiopulmonary Bypass
Nonlinear complexity measures computed from beat-to-beat arterial BP dynamics have shown associations with standard cardiac surgical risk indices. They reflect the physiological adaptability of a system and has been proposed as dynamical biomarkers of overall health status.
Tranexamic Acid and Convulsive Seizures After Off-pump Coronary Artery Bypass Surgery: the Role of Renal Insufficiency
There is evidence that, in adult cardiac surgical patients undergoing on-pump procedures, tranexamic acid (TXA) dose-dependently increases the risk of convulsive seizure (CS).
Norwood Procedure-Difficulty in Weaning From Cardiopulmonary Bypass and Implications for Outcomes
Difficulty weaning from cardiopulmonary bypass (CPB) or the need to return to CPB (collectively D-CPB) may occur after the Norwood procedure. We sought to evaluate the relationship between D-CBP and survival.
The Effect of Steroids in Patients Undergoing Cardiopulmonary Bypass: An Individual Patient Meta-Analysis of Two Randomized Trials
Steroids suppress the inflammatory response to cardiopulmonary bypass, but the impact on death at 30 days, myocardial infarction or injury, stroke, renal failure, respiratory failure, new atrial fibrillation, transfusion requirement, infection, and length of intensive care unit (ICU) and hospital stays are uncertain.
Extracorporeal Gas Exchange: When To Start And How To End?
In the last decade, primarily following the H1N1 pandemics , the extracorporeal respiratory assist is increasingly used [2, 3]. The acronym “ECMO”, i.e., ExtraCorporeal Membrane Oxygenation, is, however, somehow misleading as the artificial extracorporeal assist may affect both oxygenation and CO2 removal, as well as the hemodynamics, depending on how it is applied.
Perioperative Anemia Management as Part of PBM in Cardiac Surgery – A Narrative Updated Review
Anemia is common in patients with cardiac disease. Iron deficiency is the cause of anemia in about 80% of all cases. Preoperative anemia is associated with an increased morbidity and mortality in patients undergoing cardiac surgery.