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Has Venoarterial Ecmo Been Underutilized in Covid-19 Patients?

This outbreak of infectious disease could enable an improved understanding of ARDS and a more precise use of therapeutics as ECMO and different configurations with a tailor-made treatment.

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How I Approach Weaning from Venoarterial Ecmo

In this article, we review our standardized approach to VA-ECMO weaning in adult patients.

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American Experience with Extracorporeal Support in Covid-19 Patients: Early Outcomes from a Single Institution

As the world learned about Covid-19, the application of ECMO also evolved as health systems in the United States had some time to prepare. We report our initial experience using extracorporeal support for Covid-19 patients with the resource challenges that attend a worldwide pandemic.

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The role of ECMO in COVID-19: Can it Provide Rescue Therapy in Those Who Are Critically Ill?

Our understanding of COVID‐19 is ever‐changing and the need for intensive care beds is rising, which means that ECMO will surely play a key role in the near future.

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Antifactor Xa Monitoring and Hematologic Complications of Pediatric Extracorporeal Membrane Oxygenation

Management of anticoagulation based on anti-Xa levels appears to be as effective as management based on ACT results.

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Neurological Pupil index for Early Prognostication After Venoarterial Extracorporeal Membrane Oxygenation

Quantitative NPi alone had excellent ability to predict a poor outcome from day 1 after VA-ECMO insertion, with no false positives. Combining NPi and 12-h PREDICT-VA ECMO score increased the sensitivity of outcome prediction, while maintaining 100% specificity.

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Thrombotic Risk in Central Venoarterial Extracorporeal Membrane Oxygenation Post Cardiac Surgery

Stasis is the predominant risk factor for intracardiac thrombosis. This occurs rapidly and the outcome is poor. As a result, we suggest early left ventricular decompression. Conventional management of post-bypass coagulopathy seems safe if the aortic valve is opening.

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Air in Extracorporeal Membrane Oxygenation: Can Never be Overemphasized

Air in the extracorporeal membrane oxygenation circuit should never be overemphasized, especially during special procedures.

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Childhood Extracorporeal Membrane Oxygenation Survivors: Parents Highlight Need for Structured Follow-Up and Support After Hospital Discharge

A proportion of children who have undergone extracorporeal membrane oxygenation treatment have needs that are not being met, with variable access to service provision.

coronavirus covid19_1580x485

ECMO Use in COVID-19: Lessons from Past Respiratory Virus Outbreaks—a Narrative Review

Here, we review the experience with the use of ECMO in the past respiratory virus outbreaks and discuss potential role for ECMO in COVID-19.


Safety and Efficacy of a Novel Pneumatically Driven Extracorporeal Membrane Oxygenation Device

The pneumatically driven ECMO device provided excellent safety and physiologic efficacy in a 7-day sheep experiment without visible clotting, hemolysis, or sustained reductions in fibrinogen or platelets.

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Validation of the ‘Paediatric Extracorporeal Membrane Oxygenation Prediction’ Model in a UK Extracorporeal Membrane Oxygenation Centre

This small single-centre study with a small number of events was unable to validate the paediatric extracorporeal membrane oxygenation prediction-model of risk-adjustment. Although this remains the most promising of all the available models, further validation in larger data sets and/or refinement may be required before widespread use.

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Fixed and Dilated Pupils, Not a Contraindication for Extracorporeal Support: a Case Series

The patients described demonstrate that fixed and dilated pupils are not a contraindication for extracorporeal support in select patients.

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Association Between Low pH and Unfavorable Neurological Outcome among Out-of-hospital Cardiac Arrest Patients Treated by Extracorporeal CPR: a Prospective Observational Cohort Study in Japan

This multi-institutional observational study showed that low pH value (< 7.03) before the implementation of ECPR was associated with 1 month unfavorable neurological outcome among OHCA patients treated with ECPR. It may be helpful to consider the candidate for ECPR.

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Cannula and Circuit Management in Peripheral Extracorporeal Membrane Oxygenation: An International Survey of 45 Countries

An evidence-based guideline would be beneficial to improve ECMO line management according to 78% of respondents. Evidence gaps were identified for antiseptic agents, dressing products and regimens, securement methods, and needleless valves. Future research addressing these areas may provide opportunities for consensus guideline development and practice improvement.

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Extracorporeal Membrane Oxygenation Support for Pediatric Burn Patients: Is It Worth the Risk?

Extracorporeal membrane oxygenation could be considered as an additional level of support for the pediatric burn population, especially in the setting of respiratory failure.


Extracorporeal Oxygenation and COVID-19 Epidemic is the Membrane Fail-Safe to Cross Contamination?

We concluded that it is possible for SARS-CoV-2 to cross the membrane and aerosolize through the gas-exit port of the membrane lung. This phenomenon might be dependent on the presence of viral traces in the bloodstream and on the occurrence of fibers damage, which are both considered rare scenarios.


Veno-venous Extracorporeal Membrane Oxygenation for Respiratory Failure in COVID-19 Patients

This is 1 the first case series describing VV ECMO outcomes in COVID-19 patients. Our initial data suggest that VV ECMO can be successfully utilized in appropriately selected COVID-19 patients with advanced respiratory failure.


COVID-19 Outbreak in France: Setup and Activities of a Mobile Extracorporeal Membrane Oxygenation Team During the First 3 Weeks

The setup of a mobile ECMO team within an experienced ECMO center is feasible and may help in the treatment of COVID-19 patients.


Thrombosis and coagulopathy in COVID-19 patients requiring extracorporeal membrane oxygenation

The purpose of this editorial is to briefly discuss COVID19-associated procoagulant and anticoagulant states in the context of ECMO support.

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Turning Things Around: The Role of Prone Positioning in the Management of Acute Respiratory Failure After Cardiac Surgery

Prone positioning can be considered for the treatment of ARF after cardiac surgery to improve short-term respiratory conditions and possibly facilitate ECMO weaning.


Massive Pulmonary Embolism: Embolectomy or Extracorporeal Membrane Oxygenation?

Although surgical embolectomy continues to be the initial treatment of choice in massive pulmonary embolism with contraindications or failed fibrinolysis, the use of ECMO in these high-risk patients provides an important tool in managing this often fatal condition.

Transeptal RA to LA off load cannula with VA ECMO

How I Manage Drainage Insufficiency on Extracorporeal Membrane Oxygenation

We propose a physiology-based algorithmic approach to the management of drainage insufficiency.


Joint Society of Critical Care Medicine-Extracorporeal Life Support Organization Task Force Position Paper on the Role of the Intensivist in the Initiation and Management of Extracorporeal Membrane Oxygenation

The role of the intensivist in the care of patients on extracorporeal membrane oxygenation continues to evolve and grow, especially when knowledge and familiarity of the issues surrounding extracorporeal membrane oxygenation selection, cannulation, and management are applied.