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The Use of Extracorporeal Membrane Oxygenation in Human Immunodeficiency Virus–Positive Patients: a Review of a Multicenter Database

Survival among patients with human immunodeficiency virus infection who receive extracorporeal membrane oxygenation was less than 40%.


Mechanical Ventilation Management during Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome. An International Multicenter Prospective Cohort

Ultraprotective lung ventilation on ECMO was largely adopted across medium– to high–case volume ECMO centers. In contrast with previous observations, mechanical ventilation settings during ECMO did not impact patients’ prognosis in this context.


Extracorporeal Membrane Oxygenation Support for Postcardiotomy Cardiogenic Shock in Adult Patients: Predictors of In-Hospital Mortality and Failure to be Weaned from Extracorporeal Membrane Oxygenation

Our data suggest a reevaluation of therapeutic strategies after 60 h and again after 130 h of ECMO support.

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Anticoagulation in Neonatal ECMO: An Enigma Despite a Lot of Effort!

This review provides an overview of hemostatic alterations, anticoagulation, monitoring and management, novel anticoagulant use, and circuit modifications for neonatal ECMO. Future considerations are also presented.


Venoarterial Extracorporeal Membrane Oxygenation in Sickle Cell Disease for Urgent Cardiac Surgery

This highlights that SCD should not be a counterindication to VA-ECMO, pending multidisciplinary management.

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Methylprednisolone May be Associated with Improved Lung Compliance in Acute Respiratory Distress Syndrome Patients on Veno-Venous Extracorporeal Membrane Oxygenation

Further studies are required to identify appropriate patient selection for methylprednisolone use in patients on veno-venous extracorporeal membrane oxygenation.


Impact of Delayed Systemic Heparinization on Postoperative Bleeding and Thromboembolism During Post-Cardiotomy Extracorporeal Membrane Oxygenation in Neonates

In this retrospective analysis, the results of delayed systemic heparinization in neonatal post-cardiotomy extracorporeal membrane oxygenation could lead one to conclude that this routine is safe and favorable with low risk for thromboembolic events, reduced postoperative hemorrhage, and reduced blood product utilization.


Preparing for the Most Critically Ill Patients With COVID-19: The Potential Role of Extracorporeal Membrane Oxygenation

The WHO interim guidelines made general recommendations for treatment of ARDS in this setting, including that consideration be given to referring patients with refractory hypoxemia to expert centers capable of providing extracorporeal membrane oxygenation (ECMO).


Extracorporeal Membrane Oxygenation Support in 2019 Novel Coronavirus Disease: Indications, Timing, and Implementation

Because the evidence
for recovering from COVID-19 with ECMO is extremely limited so far, we can learn from the previous experiences in the treatment of similar severe viral pneumonia cases through retrospective literature review and data analysis.

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Extracorporeal Membrane Oxygenation Without Therapeutic Anticoagulation in Adults: A Systematic Review of the Current Literature

Further investigations are warranted to elucidate actual aspects regarding extracorporeal membrane oxygenation system performance, related adverse events and benefits associated with this management.


A Skills Acquisition Study on ECMOjo: a Screen-Based Simulator for Extracorporeal Membrane Oxygenation

The present findings show no significant dissimilarities between ECMOjo and didactic classroom-based teaching.

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Early Tracheostomy after Initiation of Venovenous Extracorporeal Membrane Oxygenation is Associated with Decreased Duration of Extracorporeal Membrane Oxygenation Support

Early tracheostomy placement is associated with decreased time on extracorporeal membrane oxygenation support and reduced extracorporeal membrane oxygenation–related costs in this cohort.


Frequency of Thrombocytopenia and Heparin-Induced Thrombocytopenia in Patients Receiving Extracorporeal Membrane Oxygenation Compared With Cardiopulmonary Bypass and the Limited Sensitivity of Pretest Probability Score

Positive predictive value of Pretest Probability Score in identifying heparin-induced thrombocytopenia was lower in extracorporeal membrane oxygenation patients. 


Use of Extracorporeal Membrane Oxygenation in Postcardiotomy Pediatric Patients: Parameters Affecting Survival

Parameters affecting mortality after extracorporeal membrane oxygenation support in pediatric postcardiotomy patient group were the presence of a syndrome, multiple runs of extracorporeal membrane oxygenation, and single-ventricular physiology.


Platelet Transfusion Practice and Related Outcomes in Pediatric Extracorporeal Membrane Oxygenation

Platelet transfusion was common in this multisite pediatric extracorporeal membrane oxygenation cohort. Platelet transfusion volume was associated with increased risk of mortality, bleeding, and thrombosis.

Transeptal RA to LA off load cannula with VA ECMO

Does Concurrent Use of Intra-Aortic Balloon Pumps Improve Survival in Patients with Cardiogenic Shock Requiring Venoarterial Extracorporeal Membrane Oxygenation?

We conclude that there was no significant improvement in survival with the concurrent use of IABP and VA-ECMO for a cardiogenic shock as compared to the use of VA-ECMO alone. However, the concurrent use of IABP with VA-ECMO improved weaning success from VA-ECMO.


Outcomes of Out-Of-Hospital Extracorporeal Membrane Oxygenation Transfers: Significance of Initiation Site and Personnel

Promising extracorporeal membrane oxygenation survival rates were observed in transferred patients.


The Hemodynamic Effect of Different Left Ventricular Unloading Techniques During Veno-Arterial Extracorporeal Life Support: a Systematic Review and Meta-Analysis

Left ventricular unloading was associated with a significant reduction in left ventricular preload parameters in the setting of veno-arterial extracorporeal life support. This effect may be most pronounced for micro-axial blood pump and atrial septostomy.


Prognostic Significance of Arterial Lactate Levels at Weaning from Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation

Increased arterial lactate levels at the time of weaning from postcardiotomy VA-ECMO increases significantly the risk of hospital mortality. Arterial lactate may be useful in guiding optimal timing of VA-ECMO weaning.

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Predictors of Neurologic Recovery in Patients Who Undergo Extracorporeal Membrane Oxygenation for Refractory Cardiac Arrest

Additional studies are indicated to further define the appropriate selection criteria for ECPR implementation.


Extracorporeal Membrane Oxygenation in the Perioperative Care of the Lung Transplant Patient

Future studies will need to improve patient selection to fully take advantage of the use of ECMO in LT while minimizing its costs.


Risk Factors of In-Hospital Mortality in Adult Postcardiotomy Cardiogenic Shock Patients Successfully Weaned from Venoarterial Extracorporeal Membrane Oxygenation

Sequential organ failure assessment score might help clinicians to predict in-hospital mortality for patients successfully weaned from venoarterial extracorporeal membrane oxygenation.


Extracorporeal Resuscitation with Carbon Monoxide Improves Renal Function by Targeting Inflammatory Pathways in Cardiac Arrest in Pigs

Our data demonstrate improved renal function by extracorporeal CO treatment in a porcine model of cardiac arrest.

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Antithrombin Supplementation in Adult Patients Receiving Extracorporeal Membrane Oxygenation

Therapeutic anticoagulation occurred more frequently following antithrombin supplementation; however, this difference was not statistically significant. More bleeding events occurred following antithrombin supplementation while observing an increase in platelet transfusions.