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Extracorporeal Membrane Oxygenation in Life-threatening Massive Pulmonary Embolism

In massive pulmonary embolism (PE) with circulatory collapse or with cardiac arrest, treatment can be difficult.

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Establishing an ECMO Program in a Developing Country: Challenges and Lessons Learned

The ECMO (extracorporeal membrane oxygenation) Program at the American University of Beirut Medical Center was established in November 2015 as the first program serving adult and pediatric population in a low-resource setting.

NextGen

Accumulations of von Willebrand Factor Within ECMO Oxygenators: Potential Indicator of Coagulation Abnormalities in Critically Ill Patients?

Clot formation within membrane oxygenators (MOs) remains a critical problem during extracorporeal membrane oxygenation (ECMO).

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Heparin-Free Extracorporeal Life Support Using Tethered Liquid Perfluorocarbon: A Feasibility and Efficacy Study

Coagulation management is the leading challenge during extracorporeal life support (ECLS) due to shear stress and foreign-surface–induced coagulation disturbance during circulation.

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Impact of Age of Packed RBC Transfusion on Oxygenation in Patients Receiving Extracorporeal Membrane Oxygenation

To determine the effect of age of packed RBCs on tissue oxygenation in children receiving extracorporeal membrane oxygenation support.

ECMO Summary

Extracorporeal Membrane Oxygenation: Indications, Technique and Contemporary Outcomes

Extracorporeal membrane oxygenation (ECMO) is an advanced form of temporary life support, to aid respiratory and/or cardiac function. It has been used since the early 1970s and is based on cardiopulmonary bypass technology and diverts venous blood through an extracorporeal circuit and returns it to the body after gas exchange through a semi-permeable membrane.

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Neurologic Outcomes in Patients Who Undergo Extracorporeal Cardiopulmonary Resuscitation

This study aimed to develop a risk prediction model for neurologic outcomes in patients who underwent extracorporeal cardiopulmonary resuscitation (ECPR).

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Left Ventricular Decompression on Veno-arterial Extracorporeal Membrane Oxygenation With Intra-aortic Balloon Counterpulsation

There has been growing recognition of the favorable and unfavorable hemodynamic effects of this therapy and recent interest in the use of other percutaneous circulatory support devices to offset some of the potentially harmful hemodynamic effects.

ECMO Summary

Structured Review of Post-cardiotomy Extracorporeal Membrane Oxygenation: Part 2 – Pediatric Patients

Veno-arterial extracorporeal membrane oxygenation (ECMO) is established therapy for short-term circulatory support for children with life-treating cardiorespiratory dysfunction.

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Discriminatory Power of Scoring Systems for Outcome Prediction in Patients With Extracorporeal Membrane Oxygenation Following Cardiovascular Surgery

Although extracorporeal membrane oxygenation (ECMO) represents a rapidly evolving treatment option in patients with refractory heart or lung failure, survival remains poor and appropriate risk stratification challenging because established risk prediction models have not been validated for this specific population.

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Dexmedetomidine Extraction by the Extracorporeal Membrane Oxygenation Circuit: Results From an in Vitro Study

Dexmedetomidine is a sedative administered to minimize distress and decrease the risk of life threatening complications in children supported with extracorporeal membrane oxygenation. The extracorporeal membrane oxygenation circuit can extract drug and decrease drug exposure, placing the patient at risk of therapeutic failure.

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Determinants of the Effect of Extracorporeal Carbon Dioxide Removal in the SUPERNOVA Trial: Implications for Trial Design

To describe the variability and determinants of the effect of extracorporeal CO2 removal (ECCO2R) on tidal volume (Vt), driving pressure (ΔP), and mechanical power (PowerRS) and to determine whether highly responsive patients can be identified for the purpose of predictive enrichment in ECCO2R trial design.

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Predicting Outcome After Out-of-Hospital Cardiac Arrest: Lactate, Need for Vasopressors, and Cytochrome c

Outcome prediction after out-of-hospital cardiac arrest (OHCA) is difficult. We hypothesized that lactate and need for vasopressors would predict outcome, and that addition of a mitochondrial biomarker would enhance performance of the tool.

lungs1012

Extracorporeal Gas Exchange: When To Start And How To End?

In the last decade, primarily following the H1N1 pandemics [1], the extracorporeal respiratory assist is increasingly used [2, 3]. The acronym “ECMO”, i.e., ExtraCorporeal Membrane Oxygenation, is, however, somehow misleading as the artificial extracorporeal assist may affect both oxygenation and CO2 removal, as well as the hemodynamics, depending on how it is applied.

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Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications: A Review

The substantial growth over the last decade in the use of extracorporeal life support for adults with acute respiratory failure reveals an enthusiasm for the technology not always consistent with the evidence. However, recent high-quality data, primarily in patients with acute respiratory distress syndrome, have made extracorporeal life support more widely accepted in clinical practice.

Emerging Indications for Extracorporeal Membrane Oxygenation in Adults with Respiratory Failure

Emerging Indications for Extracorporeal Membrane Oxygenation in Adults with Respiratory Failure

Recent advances in technology have spurred the increasing use of extracorporeal membrane oxygenation (ECMO) in patients with severe hypoxemic respiratory failure.Ultimately, with upcoming and future technological advances, there is the promise of true destination therapy, which could lead to a major paradigm shift in the management of respiratory failure.

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Mechanical Ventilation Management during ECMO for ARDS: An International Multicenter Prospective Cohort

To report current practices regarding mechanical ventilation in patients treated with extracorporeal membrane oxygenation(ECMO) for severe acute respiratory distress syndrome (ARDS) and their association with 6-month outcomes.

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Extracorporeal Membrane Oxygenation (ECMO) and the Acute Respiratory Distress Syndrome (ARDS)

We conducted a systematic literature review of animal models combining features of experimental ARDS with ECMO to better understand this situation.

Regional Cerebral Oximetry as an Indicator of Acute Brain Injury in Adults Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation-A Prospective Pilot Study

Regional Cerebral Oximetry as an Indicator of Acute Brain Injury in Adults Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation-A Prospective Pilot Study

ECMO patients that develop acute brain injuries (ABIs) are observed to have worse outcomes. We evaluated the association between rScO2 and ABI in venoarterial (VA) ECMO patients.

NextGen

Cannulae Technology & Cannulation Techniques-History & Current Trends

Bob Leblanc from Medtronic presents on cannulation trends and advances in current technology (36:21 Minutes).

ECMO: When Do You Go Too Far?

ECMO: When Do You Go Too Far?

A video presentation from the Sanibel Symposium by Paul Shuttleworth, CCP, BSN, MBA (28:11 minutes).

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Cannulation Strategies in Adult Veno-arterial and Veno-venous Extracorporeal Membrane Oxygenation: Techniques, Limitations, and Special Considerations

Veno-arterial (VA) ECMO is used in selected patients with various etiologies of cardiogenic shock and entails either central or peripheral cannulation.

ECMO Summary

An Introduction to Extracorporeal Membrane Oxygenation (ECMO)

Extracorporeal membrane oxygenation (ECMO), also known as extracorporeal life support (ECLS), is an extracorporeal technique of providing prolonged cardiac and respiratory support to persons whose heart and lungs are unable to provide an adequate amount of gas exchange or perfusion to sustain life.

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