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ADA: Autologous Platelet Gel Effectively Treats Diabetic Plantar Wounds

ADA: Autologous Platelet Gel Effectively Treats Diabetic Plantar Wounds

Use of the autologous platelet gel, AuTolo-Gel, to treat non-healing diabetic plantar surface wounds provides good volume reduction and wound healing, researchers said here yesterday at the 61st Scientific Sessions of the American Diabetes Association. Carelyn P. Fylling, MSN, with Fylling Associates in Walker, Minnesota, presented the results of a chart review conducted at six…

Procurement of Autologous Platelet Rich Gel

Procurement of Autologous Platelet Rich Gel

ABSTRACT Platelet rich gel can be used as an adjunct to homeostatic measures to control bleeding and aid in wound healing. The “Direct Draw,” intra-operative method of platelet sequestration can produce an autologous platelet rich gel that can eliminate disease associated with multiple donors. It is cost effective, easy to make and can be a…

Applications of PRP in Oral and Maxillofacial Surgery

Applications of PRP in Oral and Maxillofacial Surgery

Enhancement of Autogenous Bone Grafts PRP added to autogenous cancellous marrow graft PRP was first described for use and has documented efficacy in accelerating autogenous bone graft healing. It has been shown to improve the rate of bone formation by 1.62 to 2.18 times that of controls. It also increases the density of the bone…

Cytomedix, Inc. Receives Favorable Patent Ruling In U.S. District Court

Cytomedix, Inc. Receives Favorable Patent Ruling In U.S. District Court

LITTLE ROCK, Ark., March 26, 2004 (PRIMEZONE) — Cytomedix, Inc. (CYME:OTC.OB) today announced it has received a favorable ruling from United States District Court Judge James B. Zagel of the Northern District of Illinois affirming Cytomedix’s position regarding the scope of the claims in U.S. Patent No. 5,165,938 (the Knighton Patent), which relates to the…

The Basic Biology of Platelet Growth Factors

The Basic Biology of Platelet Growth Factors

Since 1990, medical science has recognized several components in blood which are part of the natural healing process and if added to wounded tissues or surgical sites as a concentrate have the potential to accelerate healing

Prevention of Postoperative Bleeding in Anticoagulated Patients Undergoing Oral Surgery: Use of Platelet-Rich Plasma Gel

Prevention of Postoperative Bleeding in Anticoagulated Patients Undergoing Oral Surgery: Use of Platelet-Rich Plasma Gel

Purpose:This study evaluated the effectiveness of a protocol using platelet-rich plasma (PRP) to prevent bleeding after dental extraction in patients treated with anticoagulant oral therapy. Materials and Methods:Forty patients with mechanical heart-value replacement who were treated with anticoagulant oral therapy were selected for the study. Each patient was treated with PRP gel placed into residual…

Platelet-Derived Growth Factors Enhance Proliferation of Human Stromal Stem Cells

Platelet-Derived Growth Factors Enhance Proliferation of Human Stromal Stem Cells

Studies on new procedures for bone reconstruction suggest that autologous cells seeded on a resorbable scaffold can improve the treatment of bone defects. It is important to develop culture conditions for ex vivo expansion of stromal stem cells (SSC) that do not compromise their self-renewing and differentiation capability. Bone marrow SSC and platelet gel (PG)…

Platelet Gel for Healing Cutaneous Chronic Wounds

Platelet Gel for Healing Cutaneous Chronic Wounds

Wound healing is a specific host immune response for restoration of tissue integrity. Experimental studies demonstrated an alteration of growth factors activity due to their reduced synthesis, increased degradation and inactivation. In wound healing platelets play an essential role since they are rich of alpha-granules growth factors (platelet derived growth factor–PDGF; transforming growth factor-beta–TGF-beta; vascular…

Evaluation of a New Whole-Blood Filter that Allows Preparation of Platelet Concentrates by Platelet-Rich Plasma Methods

Evaluation of a New Whole-Blood Filter that Allows Preparation of Platelet Concentrates by Platelet-Rich Plasma Methods

BACKGROUND: A novel WBC-reduction in-line whole-blood (WB) filter that does not retain platelets was evaluated to assess the filtration performance and, after processing WB by the platelet-rich plasma (PRP) method, to analyze the storage quality of filtered platelet concentrate (PC) units. STUDY DESIGN AND METHODS: To analyze the filter retention, blood was collected from random…

The Effects of Autologous Platelet Gel on Wound Healing

The Effects of Autologous Platelet Gel on Wound Healing

Abstract Laser resurfocing techniques have become a popular means of achieving rejuvenation of damaged skin. Interest is great in attempting to speed re-epithelialization and healing so that patients can return to their normal activities as quickly as possible. Previous studies have demonstrated that wounds heal more quickly when they are covered and keptmoist than when…