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Enhanced Sternal Healing Through Platelet-Rich Plasma and Biodegradable Gelatin Hydrogel

The aim of this study was to evaluate the effectiveness of the controlled release of PRP from biodegradable gelatin hydrogel for promoting healing in a rabbit ischemic sternal model.

Analysis of Platelet-Rich Plasma Extraction: Variations in Platelet and Blood Components Between 4 Common Commercial Kits

Analysis of Platelet-Rich Plasma Extraction: Variations in Platelet and Blood Components Between 4 Common Commercial Kits

Platelet-rich plasma (PRP) has been extensively used as a treatment in tissue healing in tendinopathy, muscle injury, and osteoarthritis. However, there is variation in methods of extraction, and this produces different types of PRP.

Concentrated Bone Marrow Aspirate for the Treatment of Chondral Injuries and Osteoarthritis of the Knee: A Systematic Review of Outcomes

Concentrated Bone Marrow Aspirate for the Treatment of Chondral Injuries and Osteoarthritis of the Knee: A Systematic Review of Outcomes

The purpose of this study was to provide a systematic review regarding the outcomes of bone marrow aspirate concentrate used for the treatment of chondral defects and osteoarthritis of the knee.

The Basic Science of Bone Marrow Aspirate Concentrate in Chondral Injuries

The Basic Science of Bone Marrow Aspirate Concentrate in Chondral Injuries

There has been great interest in bone marrow aspirate concentrate (BMAC) as a cost effective method in delivering mesenchymal stem cells (MSCs) to aid in the repair and regeneration of cartilage defects.

Bone Marrow Aspirate Concentrate for the Treatment of Osteochondral Lesions of the Talus: A Systematic Review of Outcomes

Bone Marrow Aspirate Concentrate for the Treatment of Osteochondral Lesions of the Talus: A Systematic Review of Outcomes

The goal of this perform a systematic review on the outcomes of bone marrow aspirate concentrate (BMAC) for the treatment of chondral defects and osteoarthritis (OA) of the talus.

Pulmonary and Systemic Vascular Resistances After Cardiopulmonary Bypass: Role of Hemolysis

Pulmonary and Systemic Vascular Resistances After Cardiopulmonary Bypass: Role of Hemolysis

Prolonged cardiopulmonary bypass (CPB) is associated with hemolysis, resulting in increased plasma oxyhemoglobin and vascular nitric oxide depletion.

Pulmonary and Systemic Vascular Resistances After Cardiopulmonary Bypass: Role of Hemolysis

Pulmonary and Systemic Vascular Resistances After Cardiopulmonary Bypass: Role of Hemolysis

Prolonged cardiopulmonary bypass (CPB) is associated with hemolysis, resulting in increased plasma oxyhemoglobin and vascular nitric oxide depletion.

Sevoflurane and Isoflurane – Pharmacokinetics, Hemodynamic Stability and Cardioprotective Effects during Cardiopulmonary Bypass

Sevoflurane and Isoflurane – Pharmacokinetics, Hemodynamic Stability and Cardioprotective Effects during Cardiopulmonary Bypass

This study aimed to evaluate the pharmacokinetic profiles of sevoflurane and isoflurane during the use of a minimized extracorporal circulation to perform coronary artery bypass graft surgery.

Adding Emulsified Isoflurane to Cardioplegia Solution Produces Cardiac Protection in a Dog Cardiopulmonary Bypass Model

Adding Emulsified Isoflurane to Cardioplegia Solution Produces Cardiac Protection in a Dog Cardiopulmonary Bypass Model

This study investigated whether caridoplegia solution with Emulsified Isoflurane (EI) could improve cardiaoprotection in a dog CPB model of great similarity to clinical settings.

Rapid Rewarming During Cardiopulmonary Bypass Is Associated With Cerebral Injury

Rapid Rewarming During Cardiopulmonary Bypass Is Associated With Cerebral Injury

Hori and colleagues [1] investigated rewarming strategies in cardiopulmonary bypass (CPB) and their relationship with plasma levels of glial fibrillary acidic protein (GFAP), a serum protein generated by ischemic or necrotic cerebral astrocytes, or both.

Moderate hypothermic circulatory arrest in total arch repair for acute type A aortic dissection: clinical safety and efficacy

Moderate hypothermic circulatory arrest in total arch repair for acute type A aortic dissection: clinical safety and efficacy

Continued debates exist regarding the optimal temperature during hypothermic circulatory arrest (HCA) in aortic arch repair for patients with type A aortic dissection (TAAD).

The response of the microcirculation to cardiac surgery

The response of the microcirculation to cardiac surgery

Cardiac surgery is associated with a wide range of microvascular derangements and with reduced tissue oxygenation.

The response of the microcirculation to cardiac surgery

The response of the microcirculation to cardiac surgery

Cardiac surgery is associated with a wide range of microvascular derangements and with reduced tissue oxygenation.

Cardioplegic or Fibrillatory Arrest for Correction of Partial and Intermediate Atrioventricular Septal Defects?

Cardioplegic or Fibrillatory Arrest for Correction of Partial and Intermediate Atrioventricular Septal Defects?

Certain congenital cardiac surgeries can be performed in ventricular fibrillation (Vfib) as an alternative to cardioplegic arrest.

Reduction in blood transfusion in a cohort of infants having cardiac surgery with cardiopulmonary bypass after instituting a goal-directed transfusion policy.

Reduction in blood transfusion in a cohort of infants having cardiac surgery with cardiopulmonary bypass after instituting a goal-directed transfusion policy.

Current trends in pediatric cardiac surgery and anesthesiology include goal-directed allogeneic blood transfusion, but few studies address the transfusion of platelets and cryoprecipitate.

Superior Myocardial Protection Using “Polarizing” Adenosine, Lidocaine, and Mg2+ Cardioplegia in Humans

Superior Myocardial Protection Using “Polarizing” Adenosine, Lidocaine, and Mg2+ Cardioplegia in Humans

Myocardial protection with current methods of cardioplegia is still incomplete (1–3).

Treatment of a Refractory Skin Ulcer Using Punch Graft and Autologous Platelet-Rich Plasma

Treatment of a Refractory Skin Ulcer Using Punch Graft and Autologous Platelet-Rich Plasma

Combining platelet-rich plasma and skin graft enhances the efficacy of treating chronic diabetic wounds by enhancing healing rate and decreasing recurrence rate.

Platelet-Rich Plasma (PRP) Treatment of Sports-Related Severe Acute Hamstring Injuries

Platelet-Rich Plasma (PRP) Treatment of Sports-Related Severe Acute Hamstring Injuries

Platelet-rich plasma (PRP) injection at the site of severe acute hamstring injury increases the healing rate and shortens the time to return to play.

The Effect of Platelet-Rich Plasma on Arthroscopic Double-Row Rotator Cuff Repair: A Clinical Study with 12-Month Follow-Up

The Effect of Platelet-Rich Plasma on Arthroscopic Double-Row Rotator Cuff Repair: A Clinical Study with 12-Month Follow-Up

The aim of the study was to assess the effect of platelet-rich plasma on arthroscopic double-row rotator cuff repair.

Platelet-Rich Plasma for Frozen Shoulder: A Case Report

Platelet-Rich Plasma for Frozen Shoulder: A Case Report

Frozen shoulder is a glenohumeral joint disorder that limits movement because of adhesion and the existence of fibrosis in the shoulder capsule.

Effectiveness of Platelet-Rich Plasma in the Treatment of Moderate Knee Osteoarthritis: A Randomized Prospective Study

Effectiveness of Platelet-Rich Plasma in the Treatment of Moderate Knee Osteoarthritis: A Randomized Prospective Study

The purpose of this study is to assess the effects of different numbers of platelet-rich plasma (PRP) applications on pain and physical function in grade three knee osteoarthritis (OA).

Intra-Articular Injection of Photo-Activated Platelet-Rich Plasma in Patients with Knee Osteoarthritis: A Double-Blind, Randomized Controlled Pilot Study

Intra-Articular Injection of Photo-Activated Platelet-Rich Plasma in Patients with Knee Osteoarthritis: A Double-Blind, Randomized Controlled Pilot Study

This pilot study assessed the feasibility, safety and symptomatic and functional change following injections of photo-activated platelet-rich plasma (PA-PRP) compared to hyaluronic acid (HA) in people with knee osteoarthritis (OA).

Using Autologous Platelet-Rich Plasma for the Treatment of Complex Fistulas

Using Autologous Platelet-Rich Plasma for the Treatment of Complex Fistulas

This study aims to demonstrate the effectiveness and safety of autologous fibrin gel rich in platelet growth factors for the treatment of complex perianal fistulas.

Using Autologous Blood to improve outcomes in Otologic Procedures (EP Video)

Using Autologous Blood to improve outcomes in Otologic Procedures (EP Video)

This presentation by Dr. Mark Widick will introduce the use of fibrin foam in ear reconstruction and briefly introduce key concepts in chronic ear disease and surgical repair (23:42 minutes).