Luc Puis, Author at Perfusion.com

In patients undergoing coronary artery bypass grafting, low and high BMI were risk factors of mortality associated with different types of morbidities, which may warrant tailored preventive approaches.

Further evaluations with multiple dose in vitro and in vivo investigations are needed before specific voriconazole dosing recommendations can be made for clinical application with extracorporeal membrane oxygenation.

Together, these results reinforce that antithrombin may not be indicated for all pediatric extracorporeal membrane oxygenation patients.

This article therefore looks to explain the role of Freedom to Speak Up Guardians and how this new role impacts on how concerns should be raised.

Systematic evaluations of pharmacokinetic alterations of drugs on ECMO that incorporate multidrug opportunistic trials, physiologically based pharmacokinetic modeling, and other methods are necessary for definitive dose recommendations.

This guideline describes prolonged extracorporeal life support (ECLS) and extracorporeal membrane oxygenation (ECMO), applicable to Pediatric respiratory failure.

It is anticipated that ECMO facilities and ECMO service providers will incorporate the certiﬁcation examination as part of their process improvement, safety, and quality assurance plans.

The use of ECLS for temporary circulatory or respiratory support in critical patients with refractory hemorrhagic shock appears feasible considering tailored ECMO management strategies.

Our findings suggest that cross-circulation can serve as a complementary approach to clinical EVLP to recover injured donor lungs that could not otherwise be utilized for transplantation, as well as a translational research platform for immunomodulation and advanced organ bioengineering.

We advocate that our multidisciplinary approach supported by multiple technologies may be associated with faster recovery and superior outcomes than conventional minimally/conventional techniques.

To prevent postoperative AKI in CKD patients, low CPB target temperature is avoided, especially for those with high preoperative serum creatinine levels.

These results emphasized the importance of blood pressure management during CPB and the importance of the duration of circulatory arrest.

In this review, we summarise the cardiac manifestations of COVID-19 infection and propose a simplified algorithm for patient management during the COVID-19 pandemic.

This suggests that ACT devices should not be used interchangeably, but cut-off values for safe anticoagulation during cardiopulmonary bypass should be determined for each type of device, particularly when switching supplier.

The results of our study show that the degree of intraoperative EEG suppression on one hand, and low rScO2 at the end of procedure on the other hand, are associated with respectively POD and POCD in patients undergoing cardiac interventions.

Despite the body of evidence to support the use of salvaged blood for transfusion, hesitation around its use still persists, with staff apprehension around set up of cell salvage equipment and general underestimation of intraoperative blood loss being key factors in its underuse.

NIRS for optimizing ECMO therapy may be reliable for monitoring global circulatory status.

The connector sensor is therefore envisioned as an affordable alternative to OCT for real-time permittivity-based monitoring of thrombogenesis at tube–connector interface.

Health-care systems should ensure adequate availability of PPE and develop additional strategies to protect health-care workers from COVID-19, particularly those from Black, Asian, and minority ethnic backgrounds.

We thus conclude that roller pumping induced platelet apoptosis and caused decreases in platelet count and aggregation after the recirculation.

In this study representing a real-life scenario, we could demonstrate that the novel hemoadsorption device (CytoSorb®) was able to effectively adsorb HEP from the circulation if integrated in a CPB circuit.

We compared intraoperative hemadsorption and methylprednisolone, with usual care, during complex cardiac surgery on CPB, for inflammatory responses, hemodynamics, and perioperative course.

This narrative review addresses both the definition, risk factors, and pathophysiology of vasoplegia and potential therapeutic interventions.

Identification of poor prognostic indicators in this study may help inform the development of guidelines for the most appropriate use of this support modality.

Posts by Luc Puis

Body Mass Index as A Tool for Optimizing Surgical Care in Coronary Artery Bypass Grafting Through Understanding Risks of Specific Complications.

Oxygenator Impact on Voriconazole in Extracorporeal Membrane Oxygenation Circuits

Antithrombin Use During Pediatric Cardiac Extracorporeal Membrane Oxygenation Admission: Insights from A National Database

Speaking Up in the Perioperative Setting

Pharmacokinetics Alterations in Critically Ill Pediatric Patients on Extracorporeal Membrane Oxygenation: A Systematic Review

Extracorporeal Life Support Organization (ELSO): 2020 Pediatric Respiratory ELSO Guideline

Development of the Adult ECMO Specialist Certification Examination

Extracorporeal Life Support in Hemorrhagic Conditions: A Systematic Review

Xenogeneic Cross-Circulation for Extracorporeal Recovery of Injured Human Lungs

Minimally Invasive Aortic Valve Replacement on Minimally Invasive Extracorporeal Circulation: Going beyond Aesthetics.

Risk Factor for Acute Kidney Injury in Patients with Chronic Kidney Disease Receiving Valve Surgery with Cardiopulmonary Bypass

Predictors of Increased Lactate in Neonatal Cardiac Surgery: The Impact of Cardiopulmonary Bypass

SARS-CoV-2 Infection and Cardiovascular Disease: COVID-19 Heart

Evaluation of Point-of-Care ACT Coagulometers and Anti-Xa Activity During Cardiopulmonary Bypass

Predicting Postoperative Delirium and Postoperative Cognitive Decline with Combined Intraoperative Electroencephalogram Monitoring and Cerebral Near-Infrared Spectroscopy in Patients Undergoing Cardiac Interventions

Selling the Role of Salvage: Cell Salvage Past and Present

Optimization of Extracorporeal Membrane Oxygenation Therapy Using Near-Infrared Spectroscopy to Assess Changes in Peripheral Circulation: A Pilot Study

Connector Sensors for Permittivity-Based Thrombus Monitoring in Extracorporeal Life Support

Risk of COVID-19 Among Front-Line Health-Care Workers and the General Community: A Prospective Cohort Study.

The Effect of Roller Head Pump on Platelet Deterioration During the Simulated Extracorporeal Circulation

Haemoadsorption: Effective in Reducing Circulating Fragments of the Endothelial Glycocalyx During Cardiopulmonary Bypass in Patients Undergoing On-Pump Cardiac Surgery?

Extracorporeal Hemadsorption versus Glucocorticoids during Cardiopulmonary Bypass: A Prospective, Randomized, Controlled Trial

Vasoplegia After Cardiopulmonary Bypass: A Narrative Review of Pathophysiology and Emerging Targeted Therapies

Post Cardiotomy Extra Corporeal Membrane Oxygenation: Australian Cohort Review