Posts by Luc Puis
Single- Versus Multidose Cardioplegia in Adult Cardiac Surgery Patients: A Meta-analysis
Del Nido decreases operative times, reperfusion fibrillation, and surge of cardiac enzymes compared with multidose cardioplegia.
Read MoreThe Effect of Continuous Ventilation on Thiol-Disulphide Homeostasis and Albumin-Adjusted Ischemia-Modified Albumin During Cardiopulmonary Bypass
Continuous ventilation during CPB caused an increase in native and total thiol levels, an earlier return of AAIMA levels, and shorter hospital stay.
Read MoreEffect of Blood Flow on Platelets, Leukocytes, and Extracellular Vesicles in Thrombosis of Simulated Neonatal Extracorporeal Circulation
Extracorporeal membrane oxygenation (ECMO) has frequent and sometimes lethal thrombotic complications.
Read MoreVacuum-assisted Venous Drainage in Adult Cardiac Surgery: a Propensity-matched Study
VAVD was associated with a reduction in blood product transfusions, and an increase in the risk of major morbidities and in-hospital deaths of the VAVD group was not observed.
Read MoreUrine Microscopy as a Biomarker of Acute Kidney Injury Following Cardiac Surgery with Cardiopulmonary Bypass
RTEC and GC in urine sample detected by microscopy is a highly specific biomarker for early AKI diagnosis after cardiac surgery.
Read MoreStructured Review of Post-cardiotomy Extracorporeal Membrane Oxygenation: Part 2—Pediatric Patients
This report, aims to present a comprehensive overview of the available literature informing patient selection, ECMO management, and in-hospital and early post-discharge outcomes in pediatric patients treated with ECMO for post-cardiotomy cardiorespiratory failure.
Read MoreStructured Review of Post-cardiotomy Extracorporeal Membrane Oxygenation: Part 1—Adult Patients
This report, aims to present a comprehensive overview of the literature with respect to the prevalence of ECMO use, patient characteristics, ECMO management, and in-hospital and early post-discharge patient outcomes for those treated for post-cardiotomy heart, lung, or heart-lung failure.
Read MoreMalignant Hyperthermia: A Clinical Review
Malignant hyperthermia (MH) is a pharmacogenetic disease of skeletal muscle that presents as a progressively worsening hypermetabolic response in susceptible individuals exposed to triggering anesthetic agents.
Read MoreAssociation of Disposable Perioperative Jackets With Surgical Site Infections in a Large Multicenter Health Care Organization
The results of this study suggest that the use of perioperative disposable jackets is not associated with reductions in SSI for clean wounds in a large multicenter health care organization and presents a fiscal burden.
Read MorePerioperative Blood Conservation: Guidelines to Practice
The formulation of clinical practice guidelines are complex, resource-intense processes for summarizing evidence-based best practices, yet alone are insufficient for translating guidelines to practice.
Read MoreExtracorporeal Life Support in Myocardial Infarction-Induced Cardiogenic Shock: Weaning Success
Emergency ECLS is a valuable option among patients with AMI-induced CS with low and intermediate IABP-SHOCK II risk scores.
Read MoreRisk Prediction in Clinical Practice: A Practical Guide for Cardiothoracic Surgeons
The prediction of a patient’s risk for disease, death, or morbidity has become an ever more essential part of modern clinical care.
Read MoreIncreased Glucose Variability Is Associated With Major Adverse Events After Coronary Artery Bypass
Increased 24-hour but not 12-hour postoperative GV after CABG is a predictor of poor outcomes. Preoperative HbA1c is not associated with MAEs after adjusting for postoperative mean glucose and GV.
Read MoreMicrocirculation Evolution in Patients on Venoarterial Extracorporeal Membrane Oxygenation for Refractory Cardiogenic Shock
Microcirculation is severely impaired in patients with refractory cardiogenic shock requiring venoarterial extracorporeal membrane oxygenation.
Read MoreEffect of Fibrinogen Concentrate vs Cryoprecipitate on Blood Component Transfusion After Cardiac Surgery The FIBRES Randomized Clinical Trial
In patients undergoing cardiac surgery who develop clinically significant bleeding and hypofibrinogenemia after cardiopulmonary bypass, fibrinogen concentrate is noninferior to cryoprecipitate with regard to number of blood components transfused in a 24-hour period post bypass.
Read MoreEarly and Long-Term Outcomes Comparing Neonates, Infants, and Preadolescents Requiring Extracorporeal Membrane Oxygenation for Heart Failure
Veno-arterial extracorporeal membrane oxygenation is a lifesaving therapeutic chance for pediatric patients in the setting of either failure to wean from cardiopulmonary bypass or failed resuscitation from cardiac arrest.
Read MoreCoronary Artery Bypass Confers Intermediate-Term Survival Benefit over Percutaneous Coronary Intervention with New-Generation Stents in Real-World Patients with Multivessel Coronary Artery Disease, Including Left Main Disease: A Retrospective Analysis of 6383 Patients
In this contemporary cohort of real-world patients with MVD, CABG was associated with increased intermediate-term survival compared to PCI with new-generation drug-eluting stents.
Read MoreAntegrade Selective Cerebral Perfusion Reduced In-hospital Mortality and Permanent Focal Neurological Deficit in Patients with Elective Aortic Arch Surgery
Elective aortic arch surgery is associated with acceptable early and late outcomes. The ASCP is associated with a significant reduction in-hospital mortality and occurrence of permanent neurological deficits.
Read MoreMiscategorization of Deaths in the US Food and Drug Administration Adverse Events Database
As the US Food and Drug Administration (FDA) moves to hasten approval of medical devices, data from postmarketing studies and registries are increasingly relied on to inform decision-making.
Read MoreEpidemiology of Acute Kidney Injury Among Paediatric Patients After Repair of Anomalous Origin of the Left Coronary Artery From the Pulmonary Artery
Acute kidney injury (AKI) is a prevalent complication after the surgical repair of paediatric cardiac defects and is associated with poor outcomes.
Read MoreNovel Use of Cangrelor with Heparin During Cardiopulmonary Bypass in Patients with Heparin-induced Thrombocytopenia who Require Cardiovascular Surgery: A Case Series
Optimal anticoagulation strategy during cardiopulmonary bypass (CPB) remains uncertain in patients with heparin-induced thrombocytopenia (HIT) who require urgent/emergent cardiac surgery.
Read MorePeak Creatinine, Cardiopulmonary Bypass and Mortality After Stage One Single-ventricle Reconstruction
It is important to identify therapies which minimise complications associated with prolonged cardiopulmonary bypass duration in high risk populations.
Read MoreProtamine
Protamine is an FDA-approved drug for use in neutralizing the effect of unfractionated heparin.
Read MoreComparison of the Efficacy of Transthoracic Cannulation into the Ascending Aorta Versus Femoral Artery Cannulation in Minimally Invasive Cardiac Surgery
Transthoracic cannulation into the ascending aorta is reliable and can be safely performed.
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