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Coronary Reoperations Without the Use of Cardiopulmonary Bypass

Background Reoperations of coronary artery surgery still carry a higher mortality and morbidity rate, compared to primary revascularization procedures. Coronary artery bypass reoperations without the use of cardiopulmonary bypass (CPB) is a potential strategy that has been developed to decrease mortality and morbidity.Materials and methods: Between 1978 and 2000, 113 patients were reoperated for coronary…

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Poly-ADP-ribose Polymerase Inhibition Protects Against Myocardial and Endothelial Reperfusion Injury After CPB

Objective: Free radical production and related cytotoxicity during ischemia and reperfusion might lead to DNA strand breakage, which activates the nuclear enzyme poly-ADP-ribose synthetase and initiates an energy-consuming and inefficient cellular metabolic cycle with transfer of the adenosine diphosphate-ribosyl moiety of nicotinamide adenine dinucleotide (NAD+) to protein acceptors. We investigated the effects of poly-ADP-ribose synthetase…

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Neuropsychometric Outcome Following Aortic Arch Surgery: A Prospective Randomized Trial of Retrograde Cerebral Perfusion

Background: Aortic surgery requiring hypothermic circulatory arrest is associated with a high incidence of brain injury. However, knowledge of neuropsychometric outcome is limited. Retrograde cerebral perfusion has become a popular adjunctive technique to hypothermic circulatory arrest. The aim of this study was to assess neuropsychometric outcome and compare the 2 techniques. Methods: In a prospective…

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The Rewarming Rate and Increased Peak Temperature Alter Neurocognitive Outcome After Cardiac Surgery

Neurocognitive dysfunction is a common complication after cardiac surgery. We evaluated in this prospective study the effect of rewarming rate on neurocognitive outcome after hypothermic cardiopulmonary bypass (CPB). After IRB approval and informed consent, 165 coronary artery bypass graft surgery patients were studied. Patients received similar surgical and anesthetic management until rewarming from hypothermic (28°–32°C)…

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Rewarm Rate After Cardiac Surgery a Major Factor in Preventing Cognitive Deficits

DURHAM, NC — May 9, 2000 — For years, surgeons have been performing successful open heart surgeries on their patients only to find that many of them suffer cognitive deficits afterwards in such areas as memory, concentration and attention, some for as long as five years after surgery. While researchers believe that more than one…

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Right Ventricular Dysfunction Predicts Heart Failure And Mortality After Myocardial Infarction

Right ventricular function is an independent predictor of mortality and heart failure in patients with left ventricular dysfunction following myocardial infarction. Previous studies have shown that right ventricular function predicts exercise capacity, autonomic imbalance and survival in patients with advanced heart failure. Investigators from multiple institutions including the Cardiovascular Division at Brigham and Women’s Hospital…

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Robotic CABG Technology Improving Slowly

Total endoscopic coronary artery bypass to multiple target sites will become a reality in the next few years,” according to Dr. Randall K. Wolf, of Ohio State University Medical Center, in Columbus. Dr. Wolf, head of the first team in the United States to use robotic endoscopic technology for heart surgery, described the progress of…

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OSU Medical Center On the Cutting Edge in Surgery

A 35-year-old married father of one became the first person to have robotic repair of a congenital heart defect at the OSU Heart Center last month. It took surgeons using robotic technology just over two and a half hours to close a small hole between the two upper chambers of the patient’s heart. In robotic…

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Closed Chest Heart Surgery Possible with Robotics System

CHICAGO – Surgeons at Columbia-Presbyterian Medical Center in New York reported here this week that they have successfully performed “closed chest surgery for atrial septal defects through four small punctures in the chest wall. Principal investigator Dr. Michael Argenziano presented his team’s findings, at the American Heart Association’s Scientific Sessions 2002, of 15 patients who…

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Rosiglitazone Appears to Reduce In-Stent Restenosis

The peroxisomal proliferator–activated receptor-gamma agonist rosiglitazone appears to reduce the risk of in-stent restenosis in atherosclerotic coronary arteries, a new study shows. Sung Hee Choi, MD, a fellow in the Division of Endocrinology in the Department of Internal Medicine, Yonsei University College of Medicine, in Seoul, Korea, presented the findings here on June 14th at…

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PTFE Monocusp Valve for RVOT Reconstruction

Patient Selection The surgical management of patients with tetralogy of Fallot and significant right ventricular outflow tract obstruction (RVOTO) remains controversial. For patients who have a congenitally small pulmonary valve annulus who are not candidates for a valve-sparing repair, there have historically been two options: (1) transannular patch or (2) valved conduit insertion. The advantage…

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1998 Perfusion Benefits Survey

Introduction: The idea for this survey was generated out of my own frustration. Our own group of Perfusionists have been negotiating with our hospital to convert to a salary method of remuneration, rather than hourly. Although we “knew” that most Perfusionists were paid by salary, there was no data available to either us, or the…

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Neurologic Symptoms After Great Saphenous Vein Harvesting for Coronary Artery Bypass Grafting

Incidence evaluation of cutaneous neurologic symptoms in the lower limbs as a new event after great saphenous vein (GSV) harvesting for coronary artery bypass grafting (CABG). Each day we harvest the GSV for CABG. Some authors have reported the onset of saphenous neuralgia complex as a new event of which we would evaluate the incidence.…

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Double Saphenous Vein Graft Patency 23 Years Following Coronary Artery Bypass Surgery

Department of Cardiac Surgery, Royal Victoria Hospital, Belfast, Northern Ireland, UK FIG. 1 Selective contrast injection into the SVG to the right coronary artery at angiography. Although the graft is ectatic, it is widely patent, supplying the distal right coronary system. FIG. 2 Selective contrast injection into the SVG to the left anterior descending artery.…

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Never Before Seen Form of Coronavirus Identified in Record Time

April 16, 2003 — After weeks of speculation, a new form of a coronavirus never before seen in humans has been confirmed as the cause of SARS (severe acute respiratory syndrome). The World Health Organization (WHO) made the formal announcement today after scientists completed experiments that replicated SARS in monkeys infected with the coronavirus. “The…

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Nonsurgical Septal Reduction Advantageous in Hypertrophic Cardiomyopathy

Nonsurgical septal reduction brings hemodynamic and morphological improvements superior to those of dual-chamber pacing in patients with hypertrophic obstructive cardiomyopathy, according to Polish researchers. In fact, lead investigator Dr. Pawel Petkow Dimitrow told Reuters Health that he favors nonsurgical septal reduction as the first approach to appropriate patients with hypertrophic obstructive. This, he said, includes…

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Serotonin, Chemotherapy Tied To Carcinoid Heart Disease Progression

Progression of heart-valve disease is linked both with higher peak urinary levels of 5-hydroxyindoleacetic acid (5-HIAA), a serotonin metabolite, and treatment with cytotoxic chemotherapy. Researchers in the United States made this finding as a result of a retrospective study identifying factors associated with progression of carcinoid heart disease. To date, these factors have been poorly…

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Age, Sex Representation Still Low In Cardiovascular Research

Elderly people and women remain under-represented relative to their disease prevalence in randomized, controlled cardiovascular trials. Their exclusion continues despite efforts to include both groups in research. North American researchers comment: “Despite growing awareness in the last decade of potential age and sex biases, there has been only limited improvement in the inclusion of elderly…

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Closure of Cardiac Right-to-left Shunts May Abolish Migraine

WESTPORT, CT (Reuters Health) – In a subgroup of patients who have severe migraine, closure of a large cardiac right-to-left shunt appears to improve or even eradicate migraine symptomatology. As reported in the November 11th issue of The Lancet, Dr. Peter T. Wilmshurst, of Royal Shrewsbury Hospital, Shrewsbury, UK, and colleagues interviewed 37 of 40…

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Silent Ischaemia And Hypertension Continue To Perplex Cardiologists

Treatment of silent ischaemia and angina pectoris is largely the same but it remains unclear whether all ischaemic episodes or only symptomatic episodes should be eliminated, Dutch cardiologists contend. The cardiologists point out that silent ischaemia has long been recognised as a distinct clinical entity and its relevance in different patient groups has been established.…

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Histological Evaluation of Sinus Augmentation Using Platelet Rich Plasma (PRP)

Abstract:The use of Platelet Rich Plasma (PRP) in conjunction with autogenous bone graft materials has recently been advocated for use in sinus augmentation surgery as a means of enhancing both quantity and quality of newly forming bone. The use of PRP is based on the premise that autogenous plasma, rich in platelets, contributes large quantities…

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Sirolimus-Eluting Stents Inhibit New and Recurrent Lesions

Sirolimus eluting stents prevent neointimal proliferation in de novo and in in-stent restenosis lesions without inducing positive vascular remodeling, according to a report in the January issue of the European Heart Journal. Previous studies have documented the reduction of late luminal renarrowing after coronary intervention associated with the use of sirolimus eluting stents (SES), the…

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Thoracic Aortic Dissection is Associated With Severe Obstructive Sleep Apnea

Patients with thoracic aortic dissection exhibit a high apnea-hypopnea index, according to study results published in the December 15th issue of the American Journal of Respiratory and Critical Care Medicine. Obstructive sleep apnea syndrome (OSAS) “is associated with the development of arterial hypertension, the main risk factor for aortic dissection and, during obstructive episodes of…

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Use of Somanetics’ INVOS Cerebral Oximeter Significantly Decreased Stroke Rate and Adverse Clinical Outcomes

Somanetics Corporation (Nasdaq: SMTS, news) today announced that the results of the first randomized, prospective and blinded study using the Company’s INVOS® Cerebral Oximeter brain oxygen monitoring system showed statistically significant reductions in both stroke and the overall number of adverse clinical outcomes when the monitoring system was used to help manage regional brain blood…