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Diverse Causes of Prolonged Mechanical Ventilation Following CABG

Diverse Causes of Prolonged Mechanical Ventilation Following CABG

Prolonged mechanical ventilation (PMV) arises from diverse causes that vary over time and in their impact on ventilation duration following coronary artery bypass grafting (CABG). Researchers from the Physician Research Network, Methodist Healthcare University Hospital, Memphis, Tennessee, United States, enrolled 400 patients undergoing CABG. Using their standardized post-operative respiratory protocol, 41.8 percent of patients could…

Ventricular-Assist Devices Help Patients Wait for Cardiac Transplantation at Hom

Ventricular-Assist Devices Help Patients Wait for Cardiac Transplantation at Hom

Patients who need ventricular assist devices (VAD) while waiting for a heart transplant can leave the hospital and go home without increasing their mortality risk. Researchers in Germany and in the United States found that patients who were sent home wearing the devices may have done better than the patients who stayed in the hospital.…

Ventricular Assistance Device May Prevent Complications During Angioplasty

Ventricular Assistance Device May Prevent Complications During Angioplasty

The Tandem Heart percutaneous left ventricular assist device (pVAD) (Cardiac Assist Technologies, Inc., Ithaca, New York) may reduce complications associated with high-risk percutaneous coronary intervention (PCI), physicians in The Netherlands report. “The increase in safety provided by the circulatory bypass may potentially allow the treatment of patients at an extremely elevated risk, thereby eventually broadening…

Platelet Storage Solution Improves the in Vitro Function of Preserved Platelet Concentrate

Platelet Storage Solution Improves the in Vitro Function of Preserved Platelet Concentrate

BACKGROUND: Stored platelets develop biochemical lesions, manifest as depressed haemostatic function, clot retraction and wound healing. ViaCyte trade mark, a proprietary experimental preservative solution (comprising D-ribose, D-glucose, Hanks solution, Hepes solution, bovine serum albumin, tic anticoagulant peptide and sterile water), was tested in comparison with the presently accepted storage solution, citrate-dextrose-phosphate-plasma (CDP-P), to evaluate its…

Deciphering Viagra’s Heart Benefit

Deciphering Viagra’s Heart Benefit

FRIDAY, March 21 (HealthScoutNews) — The impotence drug Viagra appears to help protect the heart by stimulating the release of nitric oxide in cardiac cells, shielding a healthy heart against future damage. A Virginia Commonwealth University mouse study is the first to show that the drug, used to treat erectile dysfunction, produces therapeutic levels of…

Perfusion Community Sustains Great Loss in the Death of Viktor Magnusson

Perfusion Community Sustains Great Loss in the Death of Viktor Magnusson

The perfusion community has sustained a great loss. Viktor Magnusson, Chief Perfusionist in Reykjavik, Iceland, died Wednesday August, 30th . Viktor’s background was in the biomedical engineering field. He received his perfusion training in Uppsala, Sweden. In 1986 he moved to Iceland to help start the first and only open heart surgery program in Iceland…

Vitamin C Helps Stem Cells Become Heart Cells

Vitamin C Helps Stem Cells Become Heart Cells

By Jacqueline Stenson NEW YORK (Reuters Health) – In a finding that could aid the development of new heart failure treatments, scientists have observed that vitamin C prompts mouse embryonic stem cells to transform into beating heart muscle cells. A big hope is that doctors will one day have an ample supply of healthy human…

Weaning of Rotary Blood Pump Recipients After Myocardial Recovery: A Computer Study of Changes in Cardiac Energetics

Weaning of Rotary Blood Pump Recipients After Myocardial Recovery: A Computer Study of Changes in Cardiac Energetics

BACKGROUND: Weaning of patients from mechanical cardiac support after myocardial recovery has always involved multiple, interacting factors, particularly the training of the myocardium during reduction of pump flow. Rotary pumps offer training advantages when support flow is reduced, even to nearly zero. We report a computer analysis that evaluates the work required of the heart…

What is Perfusion?  A Summary of the Different Types of Perfusion

What is Perfusion? A Summary of the Different Types of Perfusion

The term “perfusion” is derived from the French verb ‘perfuse’ meaning to ‘pour over or through’. Perfusionists employ artificial blood pumps to propel open-heart surgery patients’ blood through their body tissue, replacing the function of the heart while the cardiac surgeon operates. When a patient’s blood is continuously removed and returned through plastic tubing to…

Women Fare Worse Than Men During Coronary Artery Bypass Graft

Women Fare Worse Than Men During Coronary Artery Bypass Graft

Women who undergo coronary artery bypass graft surgery fare worse than men and are likely to be sicker when they have the surgery. Dr. Scott Woods of Bethesda Family Practice in Cincinnati, Ohio, and colleagues analyzed data from 1,742 men and 3,582 women and compared outcomes of male and female patients undergoing coronary artery bypass…

Wound Closure Technique Affects Postoperative Infection Rate

Wound Closure Technique Affects Postoperative Infection Rate

Percutaneous suturing results in fewer superficial wound infections than does intracutaneous suturing after open-heart surgery, according to results of a randomized study comparing the two techniques. “Intracutaneous suture technique has been our standard method for closing sternal wounds in cardiac surgery, mainly for cosmetic reasons,” Dr. Ivar Risnes and fellow cardiac surgeons from Rikshospitalet in…

Wound Healing Types and Stages: An Online Review

Wound Healing Types and Stages: An Online Review

Wound Healing Types: Primary Healing – Occurring when a wound is closed within a few hours of its creation. Wound edges are surgically or mechanically approximated, and collagen metabolism provides long-term strength. Delayed Primary Healing – Occurs when a poorly delineated wound is left open to protect against wound infection. The open wound allows for…

X Technologies Wins U.S. Nod for Heart Device, Clearing the Way for Acquisition by Guidant

X Technologies Wins U.S. Nod for Heart Device, Clearing the Way for Acquisition by Guidant

NEW YORK (Reuters Health) – Privately held X Technologies Inc. has won U.S. marketing clearance for a new device, fulfilling the conditions necessary for the firm to be acquired by cardiovascular device giant Guidant Corp. under a deal announced earlier this year. X Technologies’ device is used to help clear stents that clog after being…

Advocacy Group Sues FDA, Claims Agency is Withholding Risks of Xenotransplantation

Advocacy Group Sues FDA, Claims Agency is Withholding Risks of Xenotransplantation

WASHINGTON (Reuters Health) – The Campaign for Responsible Transplantation (CRT) on Monday has asked a federal district court to compel the US Food and Drug Administration (FDA) to release records detailing the potential risks of xenotransplantation that CRT officials claim the agency has but is concealing. “We want the court to rule that the FDA…

Cloned Knockout Mini-pigs Hold Potential for Organ Xenotransplantation

Cloned Knockout Mini-pigs Hold Potential for Organ Xenotransplantation

By deleting the immunogenic alpha-1,3-galactosyltransferase (GGTA1) gene in cloned miniature swine, researchers in the US and Korea appear to have moved closer to making animal-to-human organ transplantation a reality. “This [homozygous] alteration in the gene structure will likely be enough to inhibit the initial immune response, what is called hyperacute rejection, when pig organs are…

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