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Kidney Disease: Improving Global Outcomes in Neonates with Acute Kidney Injury After Cardiac Surgery

Kidney Disease: Improving Global Outcomes in Neonates with Acute Kidney Injury After Cardiac Surgery

Acute kidney injury (AKI) after cardiac surgery (CS-AKI) in children with congenital heart disease is a serious complication closely associated with high morbidity and mortality.

Bill N Cover|Mission Checklist

Toddler Neurodevelopmental Outcomes Are Associated With School-Age IQ in Children With Single Ventricle Physiology

To examine whether neurodevelopment at preschool age predicts IQ levels and needs for special education services in school-age children with single ventricle (SV) physiology.


A Systematic Literature Review and Meta-Analysis of the Effectiveness of Extracorporeal-CPR Versus Conventional-CPR for Adult Patients in Cardiac Arrest

ECPR is a sophisticated treatment option which may improve outcomes in a selected patient population in refractory cardiac arrest.


Ultrafiltration in Pediatric Cardiac Surgery Review

Ultrafiltration has some essential benefit as it is ubiquitously used at pediatric heart centers; however, the optimal protocol could be yet identified.

Bill N Cover|Mission Checklist

Large Volume Infusions of Hydroxyethyl Starch During Cardiothoracic Surgery May Be Associated With Postoperative Kidney Injury: Propensity-Matched Analysis

Intraoperative use of HES was not associated with postoperative AKI following CPB.


Targeted Temperature Management in Patients Undergoing Extracorporeal Life Support After Out-Of-Hospital Cardiac Arrest: An EURO-ELSO 2018 Annual Conference Survey

Targeted temperature management and extracorporeal life support, particularly extracorporeal membrane oxygenation in patients undergoing cardiopulmonary resuscitation, represent outcome-enhancing strategies for patients following in- and out-of-hospital cardiac arrest.


Serum Levels of Interleukin-6, Interleukin-8, Interleukin-10, and Tumor Necrosis Factor-α, Renal Function Biochemical Parameters and Clinical Outcomes in Pediatric Cardiopulmonary Bypass Surgery

Higher circulatory pro-inflammatory cytokine level is associated with adverse outcomes such as increased intensive care unit stay and longer mechanical ventilation time in pediatric patients.


Fresh Frozen Plasma versus Crystalloid Priming of Cardiopulmonary Bypass Circuit in Pediatric Surgery: A Randomized Clinical Trial

The results demonstrate that in infants and children, priming CPB with crystalloids does not result in a different risk of postoperative bleeding and need for transfusion of allogeneic blood products.


Endothelialization of Cardiovascular Devices

Endothelialization of cardiovascular implants, including heart valves, vascular stents and vascular grafts is crucial to solve many problems in our health care system.


Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation in Patients Aged 70 Years or Older

There is uncertainty whether venoarterial extracorporeal membrane oxygenation (VA-ECMO) should be used in older patients with cardiopulmonary failure after cardiac surgery.


Axillary Intraaortic Balloon Pump Rupture and Cerebral Embolism Because of Helium Leak


Centers of Excellence: Are There Standards?

Centers of Excellence (CoEs) are intended to label hospitals that have met certain quality, process, volume and infrastructure guidelines.

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Anticoagulation With an Inhibitor of Factors XIa and XIIa During Cardiopulmonary Bypass

Preclinical animal models used in this study showed that Ir-CPI is an effective and safe antithrombotic agent that provides a clinically relevant approach to thrombosis prevention in bypass systems, including highly thrombogenic CPB.


Mini-extracorporeal Circulation Surgery Produces Less Inflammation than Off-pump Coronary Surgery

Both off-pump coronary artery bypass grafting surgery (OPCABG) and mini-extracorporeal circulation (MECC) have been associated with lower morbidity and mortality and less inflammation than conventional cardiopulmonary bypass.

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Computational Investigation of Hemodynamics in Hardshell Venous Reservoirs: A Comparative Study

Extracorporeal circulation using heart‐lung‐machines is associated with a profound activation of corpuscular and plasmatic components of circulating blood.

Bill N Cover|Mission Checklist

Life Expectancy and Mortality Rates in the United States, 1959-2017

US life expectancy has not kept pace with that of other wealthy countries and is now decreasing.

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Early and Late Outcomes of Aortic Surgery Under Hypothermic Circulatory Arrest in the Elderly: a Single Center Study

Aortic surgery with circulatory arrest in the elderly demonstrated favorable early and late results when compared with younger individuals.


Survey of Contemporary Cardiac Surgery Intensive Care Unit Models in the United States

Cardiothoracic ICU models vary widely in the United States, with almost half being open, often with no in-house coverage.

VAD|Nov 20|Paul

Developments in Pediatric Ventricular Assist Device Support

Mechanical support devices have revolutionized the management of circulatory failure.

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Role of Intraoperative Transesophageal Echocardiography in Cardiac Surgery: an Observational Study

This study is based on the hypothesis that the routine use of transesophageal echocardiography in cardiac surgery will influence the surgical decision taken by the surgeon intra-operatively in Kasr-Alainy hospitals.


Effect of Sugammadex on Coagulation as Detected by Rotational Thromboelastometry in Morbidly Obese Patients

Sugammadex produces a slight effect on coagulation in morbidly obese patients, without increasing the risk for postoperative bleeding.


Perioperative Covert Stroke in Patients Undergoing Non-cardiac Surgery (NeuroVISION): a Prospective Cohort Study

Perioperative covert stroke is associated with an increased risk of cognitive decline 1 year after non-cardiac surgery, and perioperative covert stroke occurred in one in 14 patients aged 65 years and older undergoing non-cardiac surgery.


Whole Blood Platelet Aggregation Kinetics Under Cardiopulmonary Bypass: A Pilot Study

Assessing the platelets’ functional status during surgery on cardiopulmonary bypass is challenging.

Bill N Cover|Mission Checklist

Trials Focusing on Prevention and Treatment of Delirium After Cardiac Surgery: A systematic Review of Randomized Evidence

This systematic review aimed to gather and summarize the existing evidence from randomized trials concerning interventions studied in the prevention or treatment of delirium in adult patients undergoing cardiac surgery.

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