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Bill N Cover|Mission Checklist

Effect of Preoperative Education and ICU Tour on Patient and Family Satisfaction and Anxiety in the Intensive Care Unit after Elective Cardiac Surgery: a Randomised Controlled Trial

Providing comprehensive preoperative information about ICU to elective cardiac surgical patients improved patient and family satisfaction levels and may decrease patients’ anxiety levels.


Massive Pulmonary Embolism: Embolectomy or Extracorporeal Membrane Oxygenation?

Although surgical embolectomy continues to be the initial treatment of choice in massive pulmonary embolism with contraindications or failed fibrinolysis, the use of ECMO in these high-risk patients provides an important tool in managing this often fatal condition.


Intra-Operative Hyperoxia and the Risk of Delirium in Elderly Patients after Cardiac Surgery

We conclude that CBP hyperoxia episodes may be a risk factor associated with the occurrence of postoperative delirium.

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Clinical Application of a New Ternary Polymer, SEC-1 coat™, for Pediatric Cardiopulmonary Bypass Circuits: a Prospective Randomized Pilot Study

SEC-1 coat™ for cardiopulmonary bypass circuits have good biocompatibility with regard to platelet preservation and in terms of attenuating inflammatory reaction or coagulation activation during pediatric cardiac surgery.


Effects of Erythropoietin on Lung Injury Induced by Cardiopulmonary Bypass After Cardiac Surgery

Preoperative EPO injection reduced lung injury and promoted lung function in patients who underwent CPB. The protection effect of EPO may be associated with inhibition of inflammatory response.


Hemostatis Analyzer-Supported Hemotherapy Algorithm in Cardiac Surgery: Protocol for a Randomized Controlled Monocentric Trial

Because of the comparability of the Quantra sonorheometry system with the ROTEM measurement methods, the existing hemotherapy treatment algorithm can be adapted to the Quantra device with proof of noninferiority.

Bill N Cover|Mission Checklist

Mortality Prediction After Cardiac Surgery: Higgins’ Intensive Care Unit Admission Score Revisited

Eleven variables available on admission to the ICU can be used for the prediction of 30-day mortality after cardiac surgery. The model performance was better than those of general intensive care risk adjustment models used in cardiac surgical intensive care and also avoided the subjective assessment of the cause of admission.

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Dextran- Versus Crystalloid-Based Prime in Cardiac Surgery: A Prospective Randomized Pilot Study

Our results suggest that a hyperoncotic dextran-based priming solution preserves intraoperative COP compared to crystalloid prime. Larger studies with clinically valid endpoints are necessary to evaluate hyperoncotic prime solutions further.


Biomarker Dynamics in Cardiac Surgery: a Prospective Observational Study on MR-proADM, MR-proANP, hs-CRP and sP-selectin Plasma Levels in the Perioperative Period

The findings in this study may help to understand the physiology of the biomarkers analysed and their response to cardiac surgical trauma including CPB. Furthermore, these findings will guide us in further research on the clinical usefulness of these biomarkers.

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Transfusion Use and Hemoglobin Levels by Blood Conservation Method Post Cardiopulmonary Bypass

Although Online-MUF does not appear to reduce blood transfusion, larger prospective randomized controlled studies are required for confirmation.


Vasopressor and Inotrope Therapy in Cardiac Critical Care

In this review, we discuss the pharmacology and evidence-based use of vasopressor and inotrope drugs in critically ill patients, with a focus on the CICU population.

Transeptal RA to LA off load cannula with VA ECMO

How I Manage Drainage Insufficiency on Extracorporeal Membrane Oxygenation

We propose a physiology-based algorithmic approach to the management of drainage insufficiency.


Joint Society of Critical Care Medicine-Extracorporeal Life Support Organization Task Force Position Paper on the Role of the Intensivist in the Initiation and Management of Extracorporeal Membrane Oxygenation

The role of the intensivist in the care of patients on extracorporeal membrane oxygenation continues to evolve and grow, especially when knowledge and familiarity of the issues surrounding extracorporeal membrane oxygenation selection, cannulation, and management are applied.

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Venoarterial-Extracorporeal Membrane Oxygenation Without Routine Systemic Anticoagulation Decreases Adverse Events

Patients supported on VA-ECMO without other indications for anticoagulation can be treated without systemic anticoagulation during their VA-ECMO course.


Artificial Intelligence and Machine Learning in Cardiovascular Health Care

Although there is an expanding body of literature on AI and ML in cardiovascular medicine, the future these fields will have in clinical practice remains to be paved.


Evaluation of Inflammation Caused by Cardiopulmonary Bypass in a Small Animal Model

In this review, we present a study focusing on the systemic inflammatory response during CPB, along with our findings.

COVID-19 Task Force

Joint Perfusion COVID-19 Task Force Webinar 5/14/2020

Join the Joint Perfusion COVID-19 Task Force for the next live webinar on Thursday, May 14 to hear from physicians from around the world on COVID-19 treatments, reopening ORs, and starting up CPB again.


Global Effort to Collect Data on Ventilated Patients With COVID-19

They called their study ECMOCARD, short for Extracorporeal Membrane Oxygenation for novel Coronavirus Acute Respiratory Disease.

COVID-19 Image

Covid-19: General Guidelines For Cardiovascular Surgeons (standard guidelines – subject to change)

Important considerations should be given to our readers regarding cardiac surgery, surgical teams, our patients, and their possible contacts.


Convalescent Plasma Transfusion for the Treatment of COVID‐19: Systematic Review

Based on the limited scientific data, CPT therapy in COVID‐19 patients appears safe, clinically effective, and reduces mortality.

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COVID-19: 10 Things I Wished I’d Known Some Months Ago

This viewpoint addresses 10 points that may be of interest both the logistics, as well as actual clinical care of critically ill COVID-19 patients.


Restarting with Covid-19: Seven Key Action Items

Leaders at NewYork-Presbyterian have created a Restart Coordination Committee to develop and execute a measured approach for the way forward.


Gas Exchange Calculation may Estimate Changes in Pulmonary Blood Flow during Veno-Arterial Extracorporeal Membrane Oxygenation in a Porcine model.

VCO2 of the lung correlated strongly with pulmonary blood flow. Our model could predict pulmonary blood flow changes within clinically acceptable margins of error.


Diagnosis and Management of Heparin-Induced Thrombocytopenia

HIT is a clinical-biological syndrome induced by IgG isotype antibodies, which almost always recognise heparin-modified platelet factor 4 (PF4/H), with intense platelet activation associated with explosive thrombin generation that can lead to venous and/or arterial thrombosis.