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How to Become a Perfusionist in the US for Foreign Students

This is a guide to becoming a perfusionist in the United States for designed for foreign students that are not US citizens.


Tranexamic Acid and Perioperative Bleeding in Children

Perioperative bleeding and blood product transfusion are associated with significant morbidity and mortality.


Comparison of Two Cardiopulmonary Bypass Strategies With a Miniaturized Tubing System: a Propensity Score–based Analysis

The existing cardiopulmonary bypass tubing system has already been significantly improved in our hospital by reducing the priming volume; thus, we further employed a new cardiopulmonary bypass strategy in children based on a miniaturized cardiopulmonary bypass circuit.


Extracorporeal Membrane Oxygenation in Life-threatening Massive Pulmonary Embolism

In massive pulmonary embolism (PE) with circulatory collapse or with cardiac arrest, treatment can be difficult.


Effectiveness of Magnesium in Preventing Shivering in Surgical Patients: A Systematic Review and Meta-analysis

Clinical trials regarding the antishivering effect of perioperative magnesium have produced inconsistent results.


Genetic Variation in the Glucocorticoid Receptor and Psychopathology After Dexamethasone Administration in Cardiac Surgery Patients

The glucocorticoid receptor (GR) agonist dexamethasone is frequently used for its anti-inflammatory properties.


Fibrinogen Concentrate as an Alternative to Cryoprecipitate in a Postcardiopulmonary Transfusion Algorithm in Infants Undergoing Cardiac Surgery

Infants undergoing cardiac surgery are at risk for bleeding and massive transfusion due to an immature coagulation system, complex surgeries, and cardiopulmonary bypass (CPB) effects.

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Del Nido Cardioplegia is Safe and Effective Myocardial Protection in Adult Patients Undergoing Cardiac Surgery: A Single Center Experience

Del Nido cardioplegia gains increasing popularity among adult cardiac surgeons.


Peritoneal Dialysis in Pediatric Postoperative Cardiac Surgical Patients

We determined the prevalence of acute kidney injury requiring peritoneal dialysis (PD), the factors associated with early PD initiation, prolonged PD and mortality among pediatric postoperative cardiac surgical patients.


Analysis of the Critical Determinants of Renal Medullary Oxygenation

We previously developed a three-dimensional computational model of oxygen transport in the renal medulla.

Acute Kidney Injury after Cardiac Surgery: Risk Factors and Novel Biomarkers

Acute Kidney Injury after Cardiac Surgery: Risk Factors and Novel Biomarkers

Acute kidney injury (AKI) is a common and severe complication after cardiac surgery. Currently, a series of novel biomarkers have favored the assessment of AKI after cardiac surgery in addition to the conventional indicators.

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Perfusion Management of Aortic Balloon Occlusion Technique in Total Arch Replacement With Frozen Elephant Trunk

To ensure both cerebral and lower body perfusion during total arch replacement with frozen elephant trunk, aortic balloon occlusion technique has been applied in some cases at our institute.


Establishing an ECMO Program in a Developing Country: Challenges and Lessons Learned

The ECMO (extracorporeal membrane oxygenation) Program at the American University of Beirut Medical Center was established in November 2015 as the first program serving adult and pediatric population in a low-resource setting.


Accumulations of von Willebrand Factor Within ECMO Oxygenators: Potential Indicator of Coagulation Abnormalities in Critically Ill Patients?

Clot formation within membrane oxygenators (MOs) remains a critical problem during extracorporeal membrane oxygenation (ECMO).


Is Blood a Necessary Component of the Perfusate During Isolated Limb Perfusion – a Randomized Controlled Trial

Isolated limb perfusion (ILP) is a treatment option for malignancies localized to an extremity and is performed by surgical isolation of the limb which is connected to an extracorporeal circulation system.

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Heparin-Free Extracorporeal Life Support Using Tethered Liquid Perfluorocarbon: A Feasibility and Efficacy Study

Coagulation management is the leading challenge during extracorporeal life support (ECLS) due to shear stress and foreign-surface–induced coagulation disturbance during circulation.


Detection and decontamination of Mycobacterium Chimaera and Other Non-tuberculosis Mycobacteria in Heater–cooler Devices Used in Cardiopulmonary Bypass: a Manufacturer and National Guidelines Summary, and a Potential Resolution to the Problem Requiring Further Investigation

Since 2011, invasive infections due to Mycobacterium chimaera have been diagnosed in patients with previous cardiac surgery.

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Intraoperative Autologous Blood Donation Leads to Fewer Transfusions in Cardiac Surgery

Blood conservation with antifibrinolytics, topical hemostatics, and strict transfusion triggers are becoming commonplace in cardiac surgery.

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Impact of Age of Packed RBC Transfusion on Oxygenation in Patients Receiving Extracorporeal Membrane Oxygenation

To determine the effect of age of packed RBCs on tissue oxygenation in children receiving extracorporeal membrane oxygenation support.

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Current Evidence and Future Directions of Tranexamic Acid Use, Efficacy, and Dosing for Major Surgical Procedures

Tranexamic acid reduces blood loss and transfusion requirements with no significant thrombotic adverse effects.


Serum Lactate Poorly Predicts Central Venous Oxygen Saturation in Critically Ill Patients: a Retrospective Cohort Study

Serum lactate and central venous oxygen saturation (ScvO2) are commonly used and commonly recommended as markers of tissue oxygenation in shock states.


Ex Vivo Heart Perfusion for 72 Hours Using Plasma Cross Circulation

Preservation of a donor heart for transplantation is limited to 6–8 hours.

Blood Utilization in Revision Versus First-Time Cardiac Surgery: An Update in the Era of Patient Blood Management

Blood Utilization in Revision Versus First-Time Cardiac Surgery: An Update in the Era of Patient Blood Management

Relative to first-time (primary) cardiac surgery, revision cardiac surgery is associated with increased transfusion requirements, but studies comparing these cohorts were performed before patient blood management (PBM) and blood conservation measures were commonplace. The current study was performed as an update to determine if this finding is still evident in the PBM era.

Nature of Cardiac Rehabilitation Around the Globe

Nature of Cardiac Rehabilitation Around the Globe

Cardiac rehabilitation (CR) is a clinically-effective but complex model of care. The purpose of this study was to characterize the nature of CR programs around the world, in relation to guideline recommendations, and compare this by World Health Organization (WHO) region.

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