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HTK CARDIOPLEGIA

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ALADIN View Drop Down
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Joined: Feb 13 2008
Location: Israel
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Posts: 2
  Quote ALADIN Quote  Post ReplyReply bullet Topic: HTK CARDIOPLEGIA
    Posted: Feb 18 2008 at 4:05am
WE WHOLD LIKE TO KNOW IF ANY ONE USING HTK CARDIPLEGIA- (CUSTODIOL)?  CAN U SHERE YOUR INFORMATION
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lavanyasekhar View Drop Down
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Joined: Nov 21 2007
Location: India
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  Quote lavanyasekhar Quote  Post ReplyReply bullet Posted: Mar 26 2008 at 5:25am
 
 Hi,
    I am Perfusionist from india, we have used cutodial for 10 patients, our results were good so far. we give at a rate of 150ml/mt/m2 for 8 mts either through pump or through the quick priming line(especially for adults) directly through the pressure bag at a temperature of 2-4degrees.our arrest interval was extented upto 65 minutes.So far it is working well, and we are satisfied using it especially for sick myocardium and cases expected to have prolonged cross clamp intervals.
 
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Phrixus View Drop Down
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Joined: Sep 07 2008
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  Quote Phrixus Quote  Post ReplyReply bullet Posted: Jun 03 2010 at 6:08pm

We are currently using the HTK solution as a primary cardioplegia at UPMC Presbyterian University Hospital in Pittsburgh, PA. I am doing some research into this as a cardioplegia agent as opposed to its intended use as an organ preservative. We typically give 2L initial dose; normally no further delivery is required. Blood gas analysis post cardioplegia reveals a serious drop in sodium (usually <126 mmol/L) accompanied by a drop in calcium (<0.96mmol/L).  While the HTK solution is designed to do this for organ preservation, I am curious as to its effects when introduced systemically through cardioplegia delivery (usually antegrade).  Any data concerning the use of HTK as a cardioplegia solution would be appreciated.

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jormoltx View Drop Down
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  Quote jormoltx Quote  Post ReplyReply bullet Posted: Mar 27 2012 at 2:07pm
In my thirty years doing pediatrics, HTK, delNido & Rebeyka have been the best formulas especially with single dosing.  Multidosing simply pumps more air into the myocardial tissues.  For many years we would rest the heart and tap the air trapped in the coronaries.  Single dosing is equal or better if one uses them.  My preference is for HTK with ischemic times over 200 minutes.  There also are some very long times with delNido but not so long with Rebeyka.
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